Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 12/20 | 0.69 |
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.41 |
| ▸ | KDM5A | P29375 | 1/20 | 0.40 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13910356 | 0.90 | GSK3B (0.68) | GSK3BKDM5AKDM4C | |
| SCHEMBL13722076 | 0.90 | GSK3B (0.56) | GSK3BNR1H4 | |
| SCHEMBL13910418 | 0.86 | GSK3B (0.77) | GSK3B | |
| SCHEMBL13910437 | 0.86 | GSK3B (0.68) | GSK3B | |
| SCHEMBL13910432 | 0.85 | GSK3B (0.74) | GSK3B | |
| SCHEMBL13910435 | 0.83 | GSK3B (0.67) | GSK3B | |
| SCHEMBL13910845 | 0.82 | GSK3B (0.83) | GSK3B | |
| SCHEMBL13910316 | 0.82 | GSK3B (1.00) | GSK3B | |
| SCHEMBL14063480 | 0.82 | GSK3B (0.69) | GSK3B | |
| SCHEMBL4034257 | 0.81 | GSK3B (1.00) | GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7427615-B2 | 3-substituted-4-pyrimidone derivatives | MITSUBISHI PHARMA CORPORATION (JP) | 2008-09-23 | — | — | US | disclosed |
| US-7427615-B2 | 3-substituted-4-pyrimidone derivatives | MITSUBISHI PHARMA CORPORATION (JP) | 2008-09-23 | — | — | US | disclosed |