Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | PSMD14 | O00487 | 2/20 | 0.33 |
| ▸ | PLA2G1B | P04054 | 2/20 | 0.33 |
| ▸ | MMP2 | P08253 | 2/20 | 0.33 |
| ▸ | ATG4B | Q9Y4P1 | 2/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27408629 | 1.00 | LMNA (0.42) | LMNAALDH1A1TSHRHSD17B10MEN1 | |
| SCHEMBL12951692 | 0.92 | LMNA (0.54) | LMNAALDH1A1TSHRHSD17B10MEN1 | |
| SCHEMBL15782388 | 0.92 | LMNA (0.54) | LMNAALDH1A1TSHRHSD17B10MEN1 | |
| SCHEMBL15782353 | 0.92 | LMNA (0.54) | LMNAALDH1A1TSHRHSD17B10MEN1 | |
| SCHEMBL14420684 | 0.89 | TSHR (0.37) | LMNAALDH1A1TSHRHSD17B10MEN1 | |
| Alcohol SCHEMBL6321490 | 0.88 | LMNA (0.45) | LMNACYP3A4CA2FDPSGPR84 | |
| SCHEMBL13177581 | 0.85 | CA2 (0.42) | LMNATSHRCA2FDPSGPR84 | |
| SCHEMBL10438223 | 0.85 | CA2 (0.42) | LMNATSHRCA2FDPSGPR84 | |
| SCHEMBL7868796 | 0.85 | CA2 (0.42) | LMNATSHRCA2FDPSGPR84 | |
| SCHEMBL18898963 | 0.85 | CA2 (0.42) | LMNATSHRCA2FDPSGPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1463529-B1 | PH-SENSITIVE POLYMERIC CONJUGATES OF AN ANTHRACYCLINE CANCEROSTATIC DRUG FOR TARGETED THERAPY | ZENTIVA KS (CZ) | 2009-08-19 | — | — | EP | disclosed |