Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27902633 | 0.78 | LMNA (0.40) | ALDH1A1LMNAUSP2 | |
| SCHEMBL5350631 | 0.71 | USP2 (0.51) | LMNAUSP2 | |
| SCHEMBL13447526 | 0.71 | USP2 (0.34) | ALDH1A1LMNAUSP2 | |
| SCHEMBL27561102 | 0.70 | LMNA (0.42) | ALDH1A1LMNAUSP2 | |
| SCHEMBL9227304 | 0.70 | — | — | |
| SCHEMBL5349184 | 0.70 | ALDH1A1 (0.32) | ALDH1A1LMNA | |
| SCHEMBL28401193 | 0.70 | USP2 (0.37) | ALDH1A1LMNAUSP2 | |
| SCHEMBL5349194 | 0.70 | ALDH1A1 (0.32) | ALDH1A1LMNA | |
| SCHEMBL6269634 | 0.69 | LMNA (0.40) | ALDH1A1LMNAUSP2 | |
| SCHEMBL116799 | 0.69 | MAPK1 (0.56) | ALDH1A1LMNAUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130022999-A1 | PROTEIN FRAGMENT COMPLEMENTATION ASSAYS FOR THE DETECTION OF BIOLOGICAL OR DRUG INTERACTIONS | ODYSSEY PHARMACEUTICALS, INC. (US) | 2013-01-24 | — | — | US | disclosed |
| US-8192944-B2 | Protein fragment complementation assays for the detection of biological or drug interactions | ODYSSEY THERA INC. (US) | 2012-06-05 | — | — | US | disclosed |
| US-20110287950-A1 | Protein fragment complementation assays for the detection of biological or drug interactions | ODYSSEY PHARMACEUTICALS, INC. (US) | 2011-11-24 | — | — | US | disclosed |
| US-7989218-B2 | Protein fragment complementation assays for the detection of biological or drug interactions | ODYSSEY THERA INC. (US) | 2011-08-02 | — | — | US | disclosed |
| US-20080145315-A1 | Protein fragment complementation assays in whole animals applications to drug efficacy, adme, cancer biology, immunology, infectious disease and gene therapy | ODYSSEY PHARMACEUTICALS, INC. (US) | 2008-06-19 | — | — | US | disclosed |
| US-7306914-B2 | Protein fragment complementation assays in whole animals applications to drug efficacy, ADME, cancer biology, immunology, infectious disease and gene therapy | ODYSSEY THERA INC. (US) | 2007-12-11 | — | — | US | disclosed |
| US-20070148682-A1 | Protein fragment complementation assays for the detection of biological or drug interactions | ODYSSEY PHARMACEUTICALS, INC. (US) | 2007-06-28 | — | — | US | disclosed |
| US-7160691-B2 | Protein fragment complementation assays for the detection of biological or drug interactions | ODYSSEY THERA INC. (US) | 2007-01-09 | — | — | US | disclosed |
| US-6929916-B2 | Protein fragment complementation assays for the detection of biological or drug interactions | ODYSSEY THERA INC. (US) | 2005-08-16 | — | — | US | disclosed |
| US-20050079547-A1 | Protein fragment complementation assays in whole animals applications to drug efficacy, ADME, cancer biology, immunology, infectious disease and gene therapy | MICHNICK STEPHEN WILLIAM WATSO (CA) | 2005-04-14 | — | — | US | disclosed |
| US-6294330-B1 | SCREENING LIGANDS OF CELLULAR RECEPTOR BY GENERATING VECTORS ENCODING FUSION PROTEINS OF FRAGMENTS OF REPORTER MOLECULE AND SUBDOMAINS OF RECEPTOR, TRANSFECTING CELLS WITH VECTORS, TESTING CELLS FOR REPORTER MOLECULE ACTIVITY | ODYSSEY PHARMACEUTICALS INC. | 2001-09-25 | — | — | US | disclosed |
| US-6270964-B1 | POLYPEPTIDE USED A DIAGNOSTIC TOOL IN GENETIC ENGINEERING | ODYSSEY PHARMACEUTICALS INC. | 2001-08-07 | — | — | US | disclosed |