Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTRB1 | P17538 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | GFER | P55789 | 1/20 | 0.50 |
| ▸ | PRCP | P42785 | 1/20 | 0.50 |
| ▸ | CTSK | P43235 | 3/20 | 0.49 |
| ▸ | CTSL | P07711 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | KDM1A | O60341 | 1/20 | 0.49 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.49 |
| ▸ | PREP | P48147 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1372342 | 1.00 | CTRB1 (0.57) | CTRB1KMT2ANPSR1TSHRL3MBTL1 | |
| SCHEMBL10784995 | 0.97 | CTRB1 (0.54) | CTRB1KMT2ANPSR1TSHRL3MBTL1 | |
| SCHEMBL24322559 | 0.93 | CTRB1 (0.58) | CTRB1KMT2ANPSR1TSHRL3MBTL1 | |
| SCHEMBL5859001 | 0.90 | CTRB1 (0.56) | CTRB1KMT2ANPSR1TSHRL3MBTL1 | |
| SCHEMBL7078577 | 0.90 | CTRB1 (0.55) | CTRB1KMT2ANPSR1TSHRL3MBTL1 | |
| SCHEMBL11448912 | 0.90 | CTRB1 (0.55) | CTRB1KMT2ANPSR1TSHRL3MBTL1 | |
| SCHEMBL27280340 | 0.87 | CTRB1 (0.60) | CTRB1KMT2ANPSR1TSHRL3MBTL1 | |
| SCHEMBL11450738 | 0.87 | CTRB1 (0.64) | CTRB1KMT2ANPSR1TSHRL3MBTL1 | |
| SCHEMBL11167632 | 0.87 | CTRB1 (0.64) | CTRB1KMT2ANPSR1TSHRL3MBTL1 | |
| SCHEMBL7106091 | 0.87 | CTRB1 (0.64) | CTRB1KMT2ANPSR1TSHRL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160263235-A1 | PEPTIDE THERAPEUTIC CONJUGATES AND USES THEREOF | ANGIOCHEM INC (CA) | 2016-09-15 | — | — | US | disclosed |
| EP-2794663-A1 | PEPTIDE THERAPEUTIC CONJUGATES AND USES THEREOF | Angiochem Inc. (CA) | 2014-10-29 | — | — | EP | disclosed |
| US-20110288011-A1 | PEPTIDE THERAPEUTIC CONJUGATES AND USES THEREOF | ANGIOCHEM INC. (CA) | 2011-11-24 | — | — | US | disclosed |
| WO-2010063124-A1 | PEPTIDE THERAPEUTIC CONJUGATES AND USES THEREOF | ANGIOCHEM INC. (CA) | 2010-06-10 | — | — | WO | disclosed |
| US-4416871-A | Inhibition by peptides of tolerance to and physical dependence on morphine | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1983-11-22 | — | — | US | disclosed |
| EP-0016136-A1 | INHIBITION BY PEPTIDES OF TOLERANCE TO AND DEPENDENCE ON MORPHINE | University of Illinois Foundation (US) | 1980-10-01 | — | — | EP | disclosed |
| WO-1980000216-A1 | INHIBITION BY PEPTIDES OF TOLERANCE TO AND DEPENDENCE ON MORPHINE | UNIV ILLINOIS (US) | 1980-02-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160263235-A1 | PEPTIDE THERAPEUTIC CONJUGATES AND USES THEREOF | VIP, SLC1A5, SLC47A1 | CTRB1 781/4885KMT2A 3365/4885NPSR1 247/4885 |
| US-20110288011-A1 | PEPTIDE THERAPEUTIC CONJUGATES AND USES THEREOF | VIP, SLC1A5, SLC47A1 | CTRB1 781/4885KMT2A 3365/4885NPSR1 247/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.