Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 3/20 | 0.38 |
| ▸ | CTSS | P25774 | 2/20 | 0.38 |
| ▸ | CTSK | P43235 | 2/20 | 0.38 |
| ▸ | CTSB | P07858 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.36 |
| ▸ | REN | P00797 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | LTA4H | P09960 | 1/20 | 0.34 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.34 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.33 |
| ▸ | KISS1R | Q969F8 | 1/20 | 0.33 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.33 |
| ▸ | LAP3 | P28838 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30093769 | 0.88 | ALDH1A1 (0.47) | CTSLCTSSCTSKCTSBALDH1A1 | |
| SCHEMBL31741227 | 0.88 | ALDH1A1 (0.47) | CTSLCTSSCTSKCTSBALDH1A1 | |
| SCHEMBL30645059 | 0.81 | CTSL (0.41) | CTSLCTSSCTSKCTSBALDH1A1 | |
| SCHEMBL18088732 | 0.81 | SLC7A5 (0.47) | ALDH1A1SCN9ALTA4HAAK1SLC7A5 | |
| SCHEMBL12938924 | 0.78 | ALDH1A1 (0.43) | ALDH1A1LTA4HKISS1RSLC7A5LAP3 | |
| SCHEMBL22651723 | 0.77 | GRN (0.37) | MAPK1 | |
| SCHEMBL31669627 | 0.77 | FOLH1 (0.40) | CTSLCTSSCTSKCTSBREN | |
| SCHEMBL14298799 | 0.76 | ALDH1A1 (0.47) | ALDH1A1KISS1RSLC7A5LAP3 | |
| SCHEMBL13096227 | 0.75 | ECE1 (0.41) | ALDH1A1LTA4HSLC7A5LAP3 | |
| SCHEMBL25455764 | 0.75 | GRN (0.35) | MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1625153-B1 | ACYLATED LYSOBACTIN-TYPE NONADEPSIPEPTIDES | AICURIS GMBH & CO KG (DE) | 2009-08-26 | — | — | EP | disclosed |