Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.41 |
| ▸ | DRD3 | P35462 | 3/20 | 0.41 |
| ▸ | DRD2 | P14416 | 2/20 | 0.41 |
| ▸ | HTR2B | P41595 | 2/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | STAT6 | P42226 | 1/20 | 0.41 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | DRD1 | P21728 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3082223 | 0.90 | MC4R (0.64) | MC4RLMNAADRA2ACYP2D6DRD3 | |
| SCHEMBL13146998 | 0.81 | MC4R (0.54) | MC4RLMNAADRA2ACYP2D6DRD3 | |
| SCHEMBL13724393 | 0.80 | MC4R (0.44) | MC4RLMNAALDH1A1RAB9A | |
| SCHEMBL3095881 | 0.79 | MC4R (0.59) | MC4RLMNAALDH1A1 | |
| SCHEMBL3095639 | 0.78 | MC4R (0.56) | MC4RLMNAALDH1A1 | |
| SCHEMBL3077931 | 0.76 | MC4R (0.73) | MC4RLMNAALDH1A1MCHR1 | |
| SCHEMBL6222224 | 0.76 | MC4R (0.64) | MC4RALDH1A1MCHR1 | |
| SCHEMBL3072120 | 0.76 | MC4R (0.64) | MC4RALDH1A1MCHR1 | |
| SCHEMBL3089926 | 0.73 | MC4R (0.57) | MC4RTSHRALDH1A1 | |
| SCHEMBL3095817 | 0.73 | MC4R (0.49) | MC4RDRD3SIGMAR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1590338-B1 | MODULATORS OF MELANOCORTIN RECEPTOR | ORE PHARMACEUTICALS INC (US) | 2009-08-26 | — | — | EP | disclosed |