Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 2/20 | 0.44 |
| ▸ | QRFPR | Q96P65 | 1/20 | 0.35 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | KLK7 | P49862 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | FLT3 | P36888 | 1/20 | 0.33 |
| ▸ | GLS | O94925 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | NAMPT | P43490 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3085659 | 0.88 | MC4R (0.55) | MC4RMAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL13723871 | 0.80 | MC4R (0.52) | MC4RALDH1A1LMNARAB9A | |
| SCHEMBL13725362 | 0.78 | MC4R (0.51) | MC4RMEN1KMT2A | |
| SCHEMBL13724467 | 0.74 | MAPK8 (0.43) | MC4RMAPK8KMT2ASMN1; SMN2 | |
| SCHEMBL4827523 | 0.73 | MC4R (0.53) | MC4RMEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL3084384 | 0.72 | MC4R (0.52) | MC4RMAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL13724506 | 0.72 | MC4R (0.46) | MC4RMAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL3089926 | 0.71 | MC4R (0.57) | MC4RMAPTTP53SMN1; SMN2HPGD | |
| SCHEMBL3095639 | 0.71 | MC4R (0.56) | MC4RMAPTSMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL3095817 | 0.69 | MC4R (0.49) | MC4RKMT2ASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1590338-B1 | MODULATORS OF MELANOCORTIN RECEPTOR | ORE PHARMACEUTICALS INC (US) | 2009-08-26 | — | — | EP | disclosed |