Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.41 |
| ▸ | MEN1 | O00255 | 5/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3077612 | 0.89 | MC4R (0.57) | MC4RKMT2AMEN1NPC1RAB9A | |
| SCHEMBL13725362 | 0.84 | MC4R (0.51) | MC4RKMT2AMEN1 | |
| SCHEMBL13724004 | 0.76 | HSD17B10 (0.44) | MC4RALDH1A1LMNAMAPT | |
| SCHEMBL3072138 | 0.72 | MC4R (0.65) | MC4R | |
| SCHEMBL13724393 | 0.72 | MC4R (0.44) | MC4RKMT2AMEN1NPC1RAB9A | |
| SCHEMBL3093327 | 0.69 | MC4R (0.54) | MC4RKMT2AMEN1NPC1RAB9A | |
| SCHEMBL3082139 | 0.68 | MC4R (0.74) | MC4R | |
| SCHEMBL3095952 | 0.66 | MC4R (0.76) | MC4RNPC1 | |
| SCHEMBL13724049 | 0.66 | MC4R (0.48) | MC4RKMT2AMEN1 | |
| SCHEMBL13724296 | 0.65 | MC4R (0.52) | MC4RKMT2AMEN1HTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1590338-B1 | MODULATORS OF MELANOCORTIN RECEPTOR | ORE PHARMACEUTICALS INC (US) | 2009-08-26 | — | — | EP | disclosed |