Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | MC4R | P32245 | 2/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | CACNA1G | O43497 | 10/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3088805 | 0.92 | MC4R (0.47) | HSD17B10CYP1A2CYP2D6CYP2C9TSHR | |
| SCHEMBL13724456 | 0.89 | MC4R (0.44) | CYP2D6MC4R | |
| SCHEMBL3095937 | 0.80 | MC4R (0.54) | MC4R | |
| SCHEMBL3095803 | 0.80 | MC4R (0.58) | HSD17B10MC4R | |
| SCHEMBL3088810 | 0.77 | MC4R (0.62) | HSD17B10MC4RMAPT | |
| SCHEMBL13724506 | 0.76 | MC4R (0.46) | MC4RMAPTLMNAALDH1A1 | |
| SCHEMBL3081882 | 0.71 | LMNA (0.45) | MC4RCACNA1GMAPTLMNATP53 | |
| SCHEMBL3823723 | 0.70 | MC4R (0.58) | HSD17B10MC4R | |
| SCHEMBL13147009 | 0.70 | MC4R (0.56) | MC4R | |
| SCHEMBL13147352 | 0.70 | MC4R (0.60) | MC4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1590338-B1 | MODULATORS OF MELANOCORTIN RECEPTOR | ORE PHARMACEUTICALS INC (US) | 2009-08-26 | — | — | EP | disclosed |