Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MLNR | O43193 | 15/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 8/20 | 0.46 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2326434 | 0.86 | HRH3 (0.49) | MLNRKMT2ACYP3A4 | |
| SCHEMBL20420969 | 0.86 | ALDH1A1 (0.49) | MLNRGAAMEN1KMT2ACYP3A4 | |
| SCHEMBL2326438 | 0.86 | HRH3 (0.49) | MLNRKMT2ACYP3A4 | |
| SCHEMBL27718923 | 0.84 | MLNR (0.57) | MLNRGAAMEN1KMT2ACYP3A4 | |
| SCHEMBL17078932 | 0.82 | KDM4E (0.53) | GAAMEN1KMT2A | |
| SCHEMBL17078496 | 0.82 | KDM4E (0.53) | GAAMEN1KMT2A | |
| SCHEMBL17078597 | 0.82 | KDM4E (0.53) | GAAMEN1KMT2A | |
| SCHEMBL5101701 | 0.82 | GRM2 (0.50) | GAAMEN1KMT2A | |
| SCHEMBL3396309 | 0.79 | LMNA (0.51) | MLNRCYP3A4 | |
| SCHEMBL3396312 | 0.79 | LMNA (0.51) | MLNRCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1858898-B1 | HYDRAZINOCARBONYL-THIENO[2,3-C]PYRAZOLES, PREPARATION METHOD, COMPOSITIONS CONTAINING SAME AND USE | AVENTIS PHARMA SA (FR) | 2009-08-26 | — | — | EP | disclosed |