Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN7 | P35236 | 13/20 | 0.68 |
| ▸ | HSPA1A | P0DMV8 | 9/20 | 0.68 |
| ▸ | HSPA8 | P11142 | 6/20 | 0.68 |
| ▸ | GAPDH | P04406 | 6/20 | 0.68 |
| ▸ | POLB | P06746 | 5/20 | 0.68 |
| ▸ | MAPT | P10636 | 5/20 | 0.68 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.68 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.68 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.68 |
| ▸ | RECQL | P46063 | 3/20 | 0.68 |
| ▸ | BLM | P54132 | 3/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.68 |
| ▸ | HPGD | P15428 | 3/20 | 0.68 |
| ▸ | THRB | P10828 | 2/20 | 0.68 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.68 |
| ▸ | APBA1 | Q02410 | 2/20 | 0.68 |
| ▸ | MASP2 | O00187 | 1/20 | 0.68 |
| ▸ | JUND | P17535 | 1/20 | 0.68 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13724800 | 0.88 | PTPN7 (0.69) | PTPN7HSPA1AHSPA8GAPDHPOLB | |
| SCHEMBL13726132 | 0.88 | PTPN7 (0.71) | PTPN7HSPA1AHSPA8GAPDHPOLB | |
| SCHEMBL13726141 | 0.80 | PTPN7 (0.87) | PTPN7HSPA1AHSPA8GAPDHPOLB | |
| SCHEMBL13726157 | 0.80 | PTPN7 (0.57) | PTPN7HSPA1AHSPA8GAPDHPOLB | |
| SCHEMBL13726142 | 0.78 | PTPN7 (0.55) | PTPN7HSPA1AHSPA8GAPDHPOLB | |
| SCHEMBL13726140 | 0.78 | PTPN7 (0.68) | PTPN7HSPA1AHSPA8GAPDHPOLB | |
| SCHEMBL13725604 | 0.78 | PTPN7 (0.65) | PTPN7HSPA1AHSPA8GAPDHPOLB | |
| SCHEMBL13725185 | 0.74 | PTPN7 (0.60) | PTPN7HSPA1AHSPA8GAPDHPOLB | |
| SCHEMBL13725206 | 0.71 | PTPN7 (0.87) | PTPN7HSPA1AHSPA8GAPDHPOLB | |
| SCHEMBL2116061 | 0.71 | PTPN7 (1.00) | PTPN7HSPA1AHSPA8GAPDHPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090203726-A1 | SUBSTITUTED TETRAHYDROQUINOLINES AS ANTIBACTERIAL AGENTS | MAXTHERA INC. (US) | 2009-08-13 | — | — | US | disclosed |
| US-20090203726-A1 | SUBSTITUTED TETRAHYDROQUINOLINES AS ANTIBACTERIAL AGENTS | MAXTHERA INC. (US) | 2009-08-13 | — | — | US | disclosed |
| WO-2009073550-A2 | SUBSTITUTED TETRAHYDROQUINOLINES AS ANTIBACTERIAL AGENTS | MAXTHERA, INC. (US) | 2009-06-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090203726-A1 | SUBSTITUTED TETRAHYDROQUINOLINES AS ANTIBACTERIAL AGENTS | NISCH, NDUFS3, SDHA | PTPN7 3898/4885HSPA1A 581/4885HSPA8 1422/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.