NDUFS3 — patent landscape

Top predicted compounds (top 20 by supporting neighbours, then confidence)

Compound	Confidence	Supporting neighbours
Auraptene (SCHEMBL2535029)	1.00	5/20
Auraptene (SCHEMBL2535034)	1.00	5/20
SCHEMBL8491443	0.56	4/20
SCHEMBL8489900	0.52	4/20
SCHEMBL8489907	0.52	4/20
SCHEMBL8489902	0.51	4/20
SCHEMBL8489908	0.51	4/20
SCHEMBL8491154	0.51	4/20
SCHEMBL8491160	0.51	4/20
SCHEMBL8491619	0.50	4/20
SCHEMBL8491624	0.50	4/20
SCHEMBL8491634	0.50	4/20
7-Prenyloxycoumarin (SCHEMBL4898255)	0.79	3/20
SCHEMBL712741	0.57	3/20
Geiparvarin (SCHEMBL2532495)	0.56	3/20
SCHEMBL6267768	0.55	3/20
SCHEMBL1095981	0.55	3/20
SCHEMBL4293165	0.55	3/20
SCHEMBL8490928	0.53	3/20
SCHEMBL8490937	0.53	3/20

Clinical trials — most relevant to NDUFS3 by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
Phase III Trial of Coenzyme Q10 in Mitochondrial Disease	PHASE3	COMPLETED
Effect of Montelukast Versus Co Enzyme in Sepsis	PHASE2/PHASE3	COMPLETED
Coenzyme Q10 as a Symptomatic Treatment in Parkinson's Disease	PHASE3	COMPLETED
A Study of Bezafibrate in Mitochondrial Myopathy	PHASE2	COMPLETED
Mitochondrial Dysfunction in the Pathophysiology and Treatment of Bipolar Disorder	PHASE2	WITHDRAWN
Parkinson's Disease Treatment With Coenzyme Q10	PHASE2	COMPLETED
Nicotinamide Riboside on Mitochondrial Function in Li-Fraumeni Syndrome	PHASE1/PHASE2	COMPLETED
Trial of Nicotinamide Riboside and Co-enzyme Q10 in Chronic Kidney Disease	PHASE2	COMPLETED
Does Clinical Treatment of Mitochondrial Dysfunction Impact Autism Spectrum Disorder (ASD)?	PHASE1	UNKNOWN
Genomic Profiling of Mitochondrial Disease - Imaging Analysis for Precise Mitochondrial Medicine	nan	COMPLETED
Tissue Sample Study for Mitochondrial Disorders	nan	ENROLLING_BY_INVITATION
Mitoquines in COPD	nan	UNKNOWN
Effect of Subtle Energy Transmission and Tao Calligraphy Mindfulness Practice on Mitochondrial DNA in Peripheral Blood Leukocytes	nan	NOT_YET_RECRUITING
MITOMICS : a Multi-OMICS Approach for the Diagnosis of Mitochondrial Diseases	nan	RECRUITING
Assessment of Follicular Fluid Level of Coenzyme Q10 in Women Undergoing ICSI	nan	UNKNOWN
North American Mitochondrial Disease Consortium Patient Registry and Biorepository (NAMDC)	nan	RECRUITING
Gastrointestinal Dysfunction in Children Affected With Mitochondrial Disorders	nan	COMPLETED
Assessing the Role of Mitochondrial Dysfunction in Primary Progressive Multiple Sclerosis	nan	UNKNOWN
The Genetics of Diabetes in Southern California Chinese Americans	nan	WITHDRAWN
Evaluation of Impact of Disease and Visual Disability on Quality of Life and Loss of Independence of Patients Living in France With Leber's Hereditary Optic Neuropathy (LHON) Through Qualitative and Quantitative Data Collection	nan	COMPLETED
The Natural History of Mitochondrial Diseases	nan	RECRUITING
A Study Into the Underlying Biochemical Pathways Involved in Parkinson's Disease, Such as Mitochondrial (Cellular Powerhouse) Dysfunction	nan	COMPLETED
Natural History Study of FDXR Mutation-related Mitochondriopathy	nan	COMPLETED
Diagnostic Odyssey Survey 2	nan	COMPLETED
Identification of New Candidate Genes in Patients With Mitochondrial Disease by High Resolution Chromosome Analysis on DNA Chip	nan	COMPLETED
Cardiac Mitochondrial Function in Explanted Human Hearts	nan	UNKNOWN
Nicotinamide Riboside and Mitochondrial Biogenesis	nan	COMPLETED
GDF-15 as a Biomarker for Mitochondrial Disease	nan	COMPLETED
Calf Muscle Strength in Mitochondrial Diseases	nan	COMPLETED
Natural History in Primary Mitochondrial Myopathies	nan	RECRUITING

Related proteins — ESM-2 sequence neighbours (a NDUFS3 binder may also engage these)

Protein	Name	Similarity
Q0MQG6	—	1.000	Q0MQG6 →
Q0MQG8	—	1.000	Q0MQG8 →
Q0MQG7	—	0.997	Q0MQG7 →
Q04350	—	0.996	Q04350 →
Q0GBY4	—	0.996	Q0GBY4 →
Q5VKP2	—	0.996	Q5VKP2 →
A3RM19	—	0.996	A3RM19 →
Q75009	—	0.995	Q75009 →
O10298	—	0.995	O10298 →
Q68671	—	0.995	Q68671 →
C4ZT97	—	0.995	C4ZT97 →
P24251	—	0.995	P24251 →
P46268	—	0.995	P46268 →
P58532	—	0.994	P58532 →
Q9YTU2	—	0.994	Q9YTU2 →
Q142H1	—	0.994	Q142H1 →
Q2LGZ2	—	0.994	Q2LGZ2 →
Q7NL66	—	0.994	Q7NL66 →
B7MC90	—	0.994	B7MC90 →
A7WNB0	—	0.994	A7WNB0 →
P19501	—	0.994	P19501 →
A1AI64	—	0.994	A1AI64 →
A7HY47	—	0.994	A7HY47 →
B1LMS1	—	0.994	B1LMS1 →
P0A6M4	—	0.994	P0A6M4 →
B1IVJ1	—	0.994	B1IVJ1 →
Q66T65	—	0.994	Q66T65 →
Q82506	—	0.994	Q82506 →
P13775	—	0.993	P13775 →
Q9LR75	—	0.993	Q9LR75 →