Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 6/20 | 0.50 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.50 |
| ▸ | ELOVL1 | Q9BW60 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | OGA | O60502 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.41 |
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
| ▸ | MTOR | P42345 | 1/20 | 0.40 |
| ▸ | SMG1 | Q96Q15 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13069962 | 0.84 | PIK3CA (0.53) | LRRK2PIK3CAELOVL1CYP2C19OGA | |
| SCHEMBL8197483 | 0.81 | PIK3CA (0.59) | LRRK2PIK3CAELOVL1CYP2C19OGA | |
| SCHEMBL21376960 | 0.81 | PIK3CA (0.50) | LRRK2PIK3CAELOVL1CYP2C19OGA | |
| SCHEMBL2459118 | 0.78 | PIK3CA (0.54) | LRRK2PIK3CAELOVL1CYP2C19OGA | |
| SCHEMBL5718308 | 0.78 | PIK3CA (0.54) | LRRK2PIK3CAELOVL1CYP2C19OGA | |
| SCHEMBL8358064 | 0.78 | PIK3CA (0.54) | LRRK2PIK3CAELOVL1CYP2C19OGA | |
| SCHEMBL3742630 | 0.78 | PIK3CA (0.57) | LRRK2PIK3CAABL1MTOR | |
| SCHEMBL13028832 | 0.77 | PIK3CA (0.50) | LRRK2PIK3CAELOVL1CYP2C19OGA | |
| SCHEMBL10154083 | 0.77 | PIK3CA (0.50) | LRRK2PIK3CACYP2C19OGAOPRM1 | |
| SCHEMBL8228263 | 0.77 | LRRK2 (0.56) | LRRK2PIK3CACYP2C19OGAOPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2705064-A1 | ACCELERATED CURE COMPOSITION CONTAINING AN ISOCYANATE FUNCTIONAL PREPOLYMER | Dow Global Technologies LLC (US) | 2014-03-12 | — | — | EP | disclosed |
| WO-2012151085-A1 | ACCELERATED CURE COMPOSITION CONTAINING AN ISOCYANATE FUNCTIONAL PREPOLYMER | DOW GLOBAL TECHNOLOGIES LLC (US) | 2012-11-08 | — | — | WO | disclosed |