Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | OGA | O60502 | 1/20 | 0.41 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.41 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.41 |
| ▸ | LRRK2 | Q5S007 | 4/20 | 0.41 |
| ▸ | ELOVL1 | Q9BW60 | 1/20 | 0.41 |
| ▸ | THRA | P10827 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13069962 | 0.90 | PIK3CA (0.53) | PIK3CAKMT2AOGAHCRTR1HCRTR2 | |
| SCHEMBL8197483 | 0.84 | PIK3CA (0.59) | PIK3CASMN1; SMN2OGAHCRTR1HCRTR2 | |
| SCHEMBL7363690 | 0.83 | AOC3 (0.54) | OPRM1OPRL1 | |
| SCHEMBL13725415 | 0.81 | LRRK2 (0.50) | PIK3CAOGAOPRM1OPRL1LRRK2 | |
| SCHEMBL13028832 | 0.80 | PIK3CA (0.50) | PIK3CASMN1; SMN2OGAHCRTR1HCRTR2 | |
| SCHEMBL27114925 | 0.79 | PIK3CA (0.40) | PIK3CAOGAHCRTR1HCRTR2OPRM1 | |
| SCHEMBL8358064 | 0.78 | PIK3CA (0.54) | PIK3CASMN1; SMN2OGAHCRTR1HCRTR2 | |
| SCHEMBL5718308 | 0.78 | PIK3CA (0.54) | PIK3CASMN1; SMN2OGAHCRTR1HCRTR2 | |
| SCHEMBL2459118 | 0.78 | PIK3CA (0.54) | PIK3CASMN1; SMN2OGAHCRTR1HCRTR2 | |
| SCHEMBL3742630 | 0.78 | PIK3CA (0.57) | PIK3CALRRK2ABL1PIK3CB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3101015-B1 | HETEROCYCLIC SULFONAMIDE DERIVATIVE AND MEDICINE COMPRISING SAME | EA PHARMA CO LTD (JP) | 2019-09-18 | — | — | EP | disclosed |