Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN7 | P35236 | 11/20 | 0.50 |
| ▸ | POLB | P06746 | 4/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | GAA | P10253 | 4/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | THRB | P10828 | 3/20 | 0.37 |
| ▸ | BLM | P54132 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.37 |
| ▸ | USP2 | O75604 | 2/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | GRK2 | P25098 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CDC25B | P30305 | 1/20 | 0.37 |
| ▸ | HSPA1A | P0DMV8 | 5/20 | 0.36 |
| ▸ | HSPA8 | P11142 | 3/20 | 0.36 |
| ▸ | CD44 | P16070 | 1/20 | 0.36 |
| ▸ | MSN | P26038 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13725184 | 0.82 | PTPN7 (0.75) | PTPN7POLBTDP1L3MBTL1KMT2A | |
| SCHEMBL13725206 | 0.65 | PTPN7 (0.87) | PTPN7POLBTDP1L3MBTL1KMT2A | |
| SCHEMBL13725695 | 0.63 | PTPN7 (0.74) | PTPN7POLBTDP1L3MBTL1KMT2A | |
| SCHEMBL13724862 | 0.63 | PTPN7 (0.76) | PTPN7POLBTDP1L3MBTL1KMT2A | |
| SCHEMBL13725212 | 0.62 | PTPN7 (0.88) | PTPN7POLBTDP1L3MBTL1KMT2A | |
| SCHEMBL13725616 | 0.62 | PTPN7 (0.89) | PTPN7POLBTDP1L3MBTL1KMT2A | |
| SCHEMBL13724823 | 0.61 | PTPN7 (0.85) | PTPN7POLBTDP1L3MBTL1KMT2A | |
| SCHEMBL13725254 | 0.60 | PTPN7 (0.84) | PTPN7POLBTDP1L3MBTL1KMT2A | |
| SCHEMBL13725608 | 0.60 | PTPN7 (0.82) | PTPN7POLBTDP1L3MBTL1KMT2A | |
| SCHEMBL13726135 | 0.59 | PTPN7 (0.81) | PTPN7POLBTDP1L3MBTL1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090203726-A1 | SUBSTITUTED TETRAHYDROQUINOLINES AS ANTIBACTERIAL AGENTS | MAXTHERA INC. (US) | 2009-08-13 | — | — | US | disclosed |
| US-20090203726-A1 | SUBSTITUTED TETRAHYDROQUINOLINES AS ANTIBACTERIAL AGENTS | MAXTHERA INC. (US) | 2009-08-13 | — | — | US | disclosed |
| WO-2009073550-A2 | SUBSTITUTED TETRAHYDROQUINOLINES AS ANTIBACTERIAL AGENTS | MAXTHERA, INC. (US) | 2009-06-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090203726-A1 | SUBSTITUTED TETRAHYDROQUINOLINES AS ANTIBACTERIAL AGENTS | NISCH, NDUFS3, SDHA | PTPN7 3898/4885POLB 1343/4885TDP1 3729/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.