Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 7/20 | 0.56 |
| ▸ | NOS3 | P29474 | 5/20 | 0.56 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.46 |
| ▸ | HTR3B | O95264 | 2/20 | 0.46 |
| ▸ | HTR3A | P46098 | 2/20 | 0.46 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.46 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.46 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.46 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.46 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.46 |
| ▸ | PLAU | P00749 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13726617 | 1.00 | NOS1 (0.56) | NOS1NOS3HTR3EHTR3BHTR3A | |
| SCHEMBL3392567 | 1.00 | NOS1 (0.56) | NOS1NOS3HTR3EHTR3BHTR3A | |
| SCHEMBL13724815 | 1.00 | NOS1 (0.56) | NOS1NOS3HTR3EHTR3BHTR3A | |
| SCHEMBL165971 | 0.90 | NOS1 (0.67) | NOS1NOS3HTR3EHTR3BHTR3A | |
| SCHEMBL165970 | 0.90 | NOS1 (0.67) | NOS1NOS3HTR3EHTR3BHTR3A | |
| SCHEMBL2348627 | 0.90 | NOS1 (0.67) | NOS1NOS3HTR3EHTR3BHTR3A | |
| SCHEMBL7046514 | 0.88 | NOS1 (0.58) | NOS1NOS3HTR3EHTR3BHTR3A | |
| SCHEMBL6650679 | 0.87 | NOS1 (0.64) | NOS1NOS3HTR3EHTR3BHTR3A | |
| SCHEMBL7051710 | 0.83 | NOS1 (0.58) | NOS1NOS3HTR3EHTR3BHTR3A | |
| SCHEMBL5703518 | 0.81 | NOS1 (0.56) | NOS1NOS3HTR3EHTR3BHTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012149639-A1 | NOVEL LATE TRANSITION METAL CATALYSTS FOR SELECTIVE POLYMER FORMATION | RYERSON UNIVERSITY (CA) | 2012-11-08 | — | — | WO | claimed |
| WO-2012149639-A1 | NOVEL LATE TRANSITION METAL CATALYSTS FOR SELECTIVE POLYMER FORMATION | RYERSON UNIVERSITY (CA) | 2012-11-08 | — | — | WO | disclosed |