SCHEMBL165971

SCHEMBL165971

CC(=Nc1ccccc1)C(C)=Nc1ccccc1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NOS1 P29475 7/20 0.67
NOS3 P29474 5/20 0.67
HTR3E A5X5Y0 2/20 0.55
HTR3B O95264 2/20 0.55
HTR3A P46098 2/20 0.55
HTR3D Q70Z44 2/20 0.55
HTR3C Q8WXA8 2/20 0.55
SLC22A2 O15244 1/20 0.55
SLC22A1 O15245 1/20 0.55
SLC22A3 O75751 1/20 0.55
PLAU P00749 1/20 0.55
MAPT P10636 2/20 0.50
KMT2A Q03164 3/20 0.48
MEN1 O00255 2/20 0.48
LMNA P02545 2/20 0.46
NFKB1 P19838 2/20 0.46
CYP1A2 P05177 1/20 0.46
ALOX15 P16050 1/20 0.46
CYP2C19 P33261 1/20 0.46
BLM P54132 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2348627 1.00 NOS1 (0.67) NOS1NOS3HTR3EHTR3BHTR3A
SCHEMBL165970 1.00 NOS1 (0.67) NOS1NOS3HTR3EHTR3BHTR3A
SCHEMBL6650679 0.97 NOS1 (0.64) NOS1NOS3HTR3EHTR3BHTR3A
SCHEMBL7046514 0.92 NOS1 (0.58) NOS1NOS3HTR3EHTR3BHTR3A
SCHEMBL7051710 0.92 NOS1 (0.58) NOS1NOS3HTR3EHTR3BHTR3A
SCHEMBL3392567 0.90 NOS1 (0.56) NOS1NOS3HTR3EHTR3BHTR3A
SCHEMBL13726615 0.90 NOS1 (0.56) NOS1NOS3HTR3EHTR3BHTR3A
SCHEMBL7591503 0.90 NOS1 (0.56) NOS1NOS3HTR3EHTR3BHTR3A
SCHEMBL7592300 0.90 NOS1 (0.56) NOS1NOS3HTR3EHTR3BHTR3A
SCHEMBL13726617 0.90 NOS1 (0.56) NOS1NOS3HTR3EHTR3BHTR3A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 329 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114890856-A Method for synthesizing 2,2' -biphenyl-1-carboxylic acid derivative 华南理工大学 2022-08-12 CN claimed
EP-1363923-B1 RHODIUM AND IRIDIUM COMPLEXES MERCK PATENT GMBH (DE) 2009-04-01 EP claimed
US-7125998-B2 Rhodium and iridium complexes MERCK PATENT GMBH (DE) 2006-10-24 US claimed
EP-1562964-B1 PALLADIUM AND PLATINUM COMPLEXES MERCK PATENT GMBH (DE) 2006-07-19 EP claimed
EP-1562964-A1 PALLADIUM AND PLATINUM COMPLEXES Covion Organic Semiconductors GmbH (DE) 2005-08-17 EP claimed
US-20040138455-A1 Rhodium and iridium complexes MERCK PATENT GMBH (DE) 2004-07-15 US claimed
WO-2004041835-A1 PALLADIUM AND PLATINUM COMPLEXES COVION ORGANIC SEMICONDUCTORS GMBH (DE) 2004-05-21 WO claimed
EP-1363923-A1 RHODIUM AND IRIDIUM COMPLEXES Covion Organic Semiconductors GmbH (DE) 2003-11-26 EP claimed
WO-2002068435-A1 RHODIUM AND IRIDIUM COMPLEXES COVION ORGANIC SEMICONDUCTORS GMBH (DE) 2002-09-06 WO claimed
US-12635401-B2 Metal complexes UDC Ireland (IE) 2026-05-19 US disclosed
US-20260070936-A1 METAL COMPLEXES UDC IRELAND LTD (IE) 2026-03-12 US disclosed
US-12544733-B2 Gas/liquid oligomerization reactor having successive zones with variable diameters IFP Energies Nouvelles (FR) 2026-02-10 US disclosed
US-12479780-B2 Oligomerisation process comprising a step of recycling a pre-cooled solvent IFP Energies Nouvelles (FR) 2025-11-25 US disclosed
US-12364960-B2 Method for oligomerization in a reactor comprising a gas/liquid double distributor IFP Energies Nouvelles (FR) 2025-07-22 US disclosed
US-20020099243-A1 Process for the hydroformylation of olefinically unsaturated compounds in a non-aqueous ionic solvent INSTITUT FRANCAIS DU PETROLE (FR) 2002-07-25 US disclosed
US-20010039363-A1 Process for hydroformylation using a catalyst based on cobalt and/or rhodium employed in a two-phase medium INSTITUT FRANCAIS DU PETROLE (FR) 2001-11-08 US disclosed
EP-1106595-A1 Improved hydroformylation process with cobalt and/or rhodium based catalysts in a biphasic medium INSTITUT FRANCAIS DU PETROLE (FR) 2001-06-13 EP disclosed
US-6166212-A Process for the synthesis of N-(hydroxyalkoxy) substituted hindered amine stabilizers CIBA SPECIALTY CHEMICALS CORPORATION (US) 2000-12-26 US disclosed
US-6015851-A MELT PROCESSABILITY THE GOODYEAR TIRE & RUBBER COMPANY (US) 2000-01-18 US disclosed
EP-0965612-A1 Rubber compositions containig bis anil compounds THE GOODYEAR TIRE & RUBBER COMPANY (US) 1999-12-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12544733-B2 Gas/liquid oligomerization reactor having successive zones with variable diameters NOD1, VAT1, DECR1 NOS1 131/4885NOS3 288/4885HTR3E 938/4885
US-20260070936-A1 METAL COMPLEXES SCO2, CBR1, CORO1C NOS1 1381/4885NOS3 2437/4885HTR3E 3608/4885
US-12635401-B2 Metal complexes SCO2, SOD1, NR4A1 NOS1 1651/4885NOS3 1133/4885HTR3E 3745/4885
US-20040138455-A1 Rhodium and iridium complexes RPIA, MPI, INPP5B NOS1 3525/4885NOS3 3548/4885HTR3E 4057/4885
US-12479780-B2 Oligomerisation process comprising a step of recycling a pre-cooled solvent COG4, PRPF40A, PRPF6 NOS1 2553/4885NOS3 2628/4885HTR3E 4033/4885
US-20020099243-A1 Process for the hydroformylation of olefinically unsaturated compounds in a non-aqueous ionic solvent NUDT1, PHOSPHO1, SRSF6 NOS1 223/4885NOS3 391/4885HTR3E 4496/4885
US-12364960-B2 Method for oligomerization in a reactor comprising a gas/liquid double distributor DUOX2, COASY, DUOX1 NOS1 1448/4885NOS3 1731/4885HTR3E 4151/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.