Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | HNF4A | P41235 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.34 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1933923 | 0.88 | TSHR (0.47) | TSHRPOLBGAATHRBHSP90AA1 | |
| SCHEMBL4650014 | 0.87 | TSHR (0.43) | TSHRPOLBHTTGAATHRB | |
| SCHEMBL5710258 | 0.85 | TSHR (0.44) | TSHRPOLBHTTGAATHRB | |
| SCHEMBL22833863 | 0.82 | TSHR (0.42) | TSHRPOLBHTTGAATHRB | |
| SCHEMBL4459975 | 0.81 | TSHR (0.44) | TSHRPOLBHTTGAATHRB | |
| SCHEMBL354095 | 0.81 | TSHR (0.43) | TSHRPOLBHTTHSP90AA1HNF4A | |
| SCHEMBL7151422 | 0.78 | MAPT (0.39) | TSHRPOLBHTTGAAKMT2A | |
| SCHEMBL1437854 | 0.78 | HTT (0.40) | TSHRPOLBHTTKMT2AMEN1 | |
| SCHEMBL1436652 | 0.78 | TSHR (0.41) | TSHRPOLBHTTKMT2AMEN1 | |
| SCHEMBL123882 | 0.78 | GPR35 (0.39) | TSHRPOLBHTTGAATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110035739-A | Dye composite comprising 12- hydroxy stearic acid, organic amine and dyestuff | 欧莱雅 | 2019-07-19 | — | — | CN | disclosed |
| EP-2705094-A1 | DISULFIDE DYES | BASF SE (DE) | 2014-03-12 | — | — | EP | disclosed |
| WO-2012150549-A1 | DISULFIDE DYES | BASF SE (DE) | 2012-11-08 | — | — | WO | disclosed |