Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL354095 | 0.89 | TSHR (0.43) | TSHRPOLBHTTKMT2AALDH1A1 | |
| SCHEMBL5710258 | 0.86 | TSHR (0.44) | TSHRPOLBHTTKMT2AMEN1 | |
| SCHEMBL4650014 | 0.85 | TSHR (0.43) | TSHRPOLBHTTKMT2AMEN1 | |
| SCHEMBL13726953 | 0.81 | TSHR (0.43) | TSHRPOLBHTTKMT2AMEN1 | |
| SCHEMBL22833863 | 0.80 | TSHR (0.42) | TSHRPOLBHTTKMT2AMEN1 | |
| SCHEMBL1436652 | 0.79 | TSHR (0.41) | TSHRPOLBHTTKMT2AMEN1 | |
| SCHEMBL1933923 | 0.79 | TSHR (0.47) | TSHRPOLBKMT2AMEN1USP2 | |
| SCHEMBL872694 | 0.78 | TSHR (0.40) | TSHRPOLBHTTGAATHRB | |
| SCHEMBL29377050 | 0.78 | TSHR (0.40) | TSHRPOLBHTTGAATHRB | |
| SCHEMBL8992757 | 0.77 | TSHR (0.42) | TSHRPOLBHTTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1311231-B1 | AGENT FOR COLOURING KERATIN-CONTAINING FIBRES COMPRISING AT LEAST ONE OXOCYCLOPENTENE DERIVATIVE | HENKEL KGAA (DE) | 2006-11-22 | — | — | EP | claimed |
| EP-1292271-B1 | AGENT FOR DYEING FIBRES CONTAINING KERATIN | HENKEL KGAA (DE) | 2006-11-08 | — | — | EP | claimed |
| EP-1292268-B1 | AGENT FOR DYEING KERATIN CONTAINING FIBERS | HENKEL KGAA (DE) | 2005-02-23 | — | — | EP | claimed |
| EP-1292271-A2 | AGENT FOR DYEING FIBRES CONTAINING KERATIN | Henkel Kommanditgesellschaft auf Aktien (DE) | 2003-03-19 | — | — | EP | claimed |
| EP-1292268-A2 | AGENT FOR DYEING KERATIN CONTAINING FIBERS | Henkel Kommanditgesellschaft auf Aktien (DE) | 2003-03-19 | — | — | EP | claimed |
| EP-1200050-A2 | DYEING AGENT FOR KERATINOUS FIBRES | Henkel Kommanditgesellschaft auf Aktien (DE) | 2002-05-02 | — | — | EP | claimed |
| WO-2001097764-A2 | AGENT FOR DYEING KERATIN CONTAINING FIBERS | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2001-12-27 | — | — | WO | claimed |
| WO-2001097754-A2 | AGENT FOR DYEING FIBRES CONTAINING KERATIN, CONTAINING AT LEAST ONE QUINOXALINE DERIVATIVE | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2001-12-27 | — | — | WO | claimed |
| WO-2001089587-A2 | AGENTS FOR DYEING FIBRES CONTAINING KERATIN | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2001-11-29 | — | — | WO | claimed |
| WO-2001089460-A2 | COLORANT FOR FIBRES CONTAINING KERATIN | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2001-11-29 | — | — | WO | claimed |
| WO-2001047485-A1 | AGENT FOR COLOURING FIBRES CONTAINING KERATIN | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2001-07-05 | — | — | WO | claimed |
| WO-2001010379-A2 | DYEING AGENT FOR KERATINOUS FIBRES | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2001-02-15 | — | — | WO | claimed |
| US-12178897-B2 | Oxidative dyeing agent for keratin fibers comprising novel dye precursor combinations | HENKEL AG & CO. KGAA (DE) | 2024-12-31 | — | — | US | disclosed |
| US-12109291-B2 | Oxidative dyeing agent for keratin fibers comprising novel dye precursor combinations | HENKEL AG & CO. KGAA (DE) | 2024-10-08 | — | — | US | disclosed |
| US-12102704-B2 | Oxidative dyeing agent for keratin fibers comprising novel dye precursor combinations | HENKEL AG & CO. KGAA (DE) | 2024-10-01 | — | — | US | disclosed |
| US-12097274-B2 | Oxidative dyeing agent for keratin fibers comprising novel dye precursor combinations | HENKEL AG & CO. KGAA (DE) | 2024-09-24 | — | — | US | disclosed |
| WO-2001089587-A2 | AGENTS FOR DYEING FIBRES CONTAINING KERATIN | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2001-11-29 | — | — | WO | disclosed |
| WO-2001047485-A1 | AGENT FOR COLOURING FIBRES CONTAINING KERATIN | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2001-07-05 | — | — | WO | disclosed |
| WO-2001010379-A2 | DYEING AGENT FOR KERATINOUS FIBRES | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2001-02-15 | — | — | WO | disclosed |
| EP-0578665-B1 | HAIR COLOURANTS WITH DIRECT DYES | HENKEL KGAA (DE) | 1994-12-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12109291-B2 | Oxidative dyeing agent for keratin fibers comprising novel dye precursor combinations | KRT18, ALDH5A1, ALDH2 | TSHR 4836/4885POLB 281/4885HTT 3812/4885 |
| US-12102704-B2 | Oxidative dyeing agent for keratin fibers comprising novel dye precursor combinations | KRT18, ALDH5A1, ALDH2 | TSHR 4819/4885POLB 304/4885HTT 3644/4885 |
| US-12097274-B2 | Oxidative dyeing agent for keratin fibers comprising novel dye precursor combinations | KRT18, ALDH5A1, COX5A | TSHR 4771/4885POLB 233/4885HTT 3275/4885 |
| US-12178897-B2 | Oxidative dyeing agent for keratin fibers comprising novel dye precursor combinations | KRT18, ALDH5A1, COX5A | TSHR 4846/4885POLB 358/4885HTT 3701/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.