Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.49 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MAPK14 | Q16539 | 8/20 | 0.46 |
| ▸ | MAPK11 | Q15759 | 7/20 | 0.46 |
| ▸ | MAPK13 | O15264 | 6/20 | 0.46 |
| ▸ | MAPK12 | P53778 | 6/20 | 0.46 |
| ▸ | GCGR | P47871 | 3/20 | 0.46 |
| ▸ | RAF1 | P04049 | 2/20 | 0.45 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.44 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.43 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.42 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13727001 | 1.00 | MKNK1 (0.49) | MKNK1NOTUMSMN1; SMN2MAPK14MAPK11 | |
| SCHEMBL12763648 | 0.98 | NOTUM (0.50) | MKNK1NOTUMSMN1; SMN2MAPK14MAPK11 | |
| SCHEMBL13726988 | 0.90 | NOTUM (0.56) | MKNK1NOTUMSMN1; SMN2MAPK14MAPK11 | |
| SCHEMBL13726961 | 0.90 | NOTUM (0.56) | MKNK1NOTUMSMN1; SMN2MAPK14MAPK11 | |
| SCHEMBL13727251 | 0.90 | NOTUM (0.56) | MKNK1NOTUMSMN1; SMN2MAPK14MAPK11 | |
| SCHEMBL13726970 | 0.90 | NOTUM (0.56) | MKNK1NOTUMSMN1; SMN2MAPK14MAPK11 | |
| SCHEMBL13078997 | 0.90 | KDM4E (0.41) | ADORA2AADORA1HSD17B10 | |
| SCHEMBL13078977 | 0.88 | KDM4E (0.40) | ADORA2AADORA1HSD17B10 | |
| SCHEMBL13726537 | 0.88 | MAPK9 (0.55) | MKNK1NOTUMSMN1; SMN2MAPK14MAPK11 | |
| SCHEMBL13726282 | 0.86 | CYP11B1 (0.51) | MKNK1SMN1; SMN2NPC1MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8586740-B2 | Quinoxaline derivative, and light-emitting element, light-emitting device, and electronic device using quinoxaline derivative | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) | 2013-11-19 | — | — | US | disclosed |
| US-20130049577-A1 | Quinoxaline Derivative, and Light-Emitting Element, Light-Emitting Device, and Electronic Device Using Quinoxaline Derivative | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. | 2013-02-28 | — | — | US | disclosed |
| US-20130049577-A1 | Quinoxaline Derivative, and Light-Emitting Element, Light-Emitting Device, and Electronic Device Using Quinoxaline Derivative | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. | 2013-02-28 | — | — | US | disclosed |
| US-8314101-B2 | Quinoxaline derivative, and light-emitting element, light-emitting device, and electronic device using quinoxaline derivative | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) | 2012-11-20 | — | — | US | disclosed |
| US-20090203704-A1 | Quinoxaline Derivative, and Light-Emitting Element, Light-Emitting Device, and Electronic Device Using Quinoxaline Derivative | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. | 2009-08-13 | — | — | US | disclosed |
| US-20090203704-A1 | Quinoxaline Derivative, and Light-Emitting Element, Light-Emitting Device, and Electronic Device Using Quinoxaline Derivative | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. | 2009-08-13 | — | — | US | disclosed |
| EP-2065378-A1 | Quinoxaline derivate, and light-emitting element, light-emitting device, and electronic device using quinoxaline derivative | Semiconductor Energy Laboratory Co, Ltd. (JP) | 2009-06-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090203704-A1 | Quinoxaline Derivative, and Light-Emitting Element, Light-Emitting Device, and Electronic Device Using Quinoxaline Derivative | PDXK, NQO1, PPOX | MKNK1 1274/4885NOTUM 3660/4885SMN1; SMN2 4090/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.