Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 2/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.42 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.42 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | PI4KA | P42356 | 1/20 | 0.38 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.38 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.38 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.38 |
| ▸ | GPR84 | Q9NQS5 | 5/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6233162 | 0.84 | XDH (0.51) | XDHPARP1FFAR3HCAR2ALDH1A1 | |
| SCHEMBL3118423 | 0.79 | XDH (0.54) | XDHPARP1HCAR2PI4KAPI4K2B | |
| SCHEMBL11661802 | 0.78 | XDH (0.56) | XDHHCAR2PI4KAPI4K2BPI4K2A | |
| SCHEMBL9845191 | 0.78 | XDH (0.40) | XDHPARP1ALDH1A1MAPK1CYP3A4 | |
| SCHEMBL1150739 | 0.77 | XDH (0.47) | XDHHCAR2ALDH1A1MAPK1CYP3A4 | |
| SCHEMBL7329904 | 0.75 | XDH (0.43) | XDHALDH1A1POLBKMT2APKM | |
| SCHEMBL4090386 | 0.73 | XDH (0.39) | XDHALDH1A1POLBKMT2APKM | |
| SCHEMBL6272728 | 0.72 | PNP (0.58) | ALDH1A1PI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL9845194 | 0.71 | POLB (0.42) | XDHALDH1A1CYP3A4CYP2C19GPR84 | |
| SCHEMBL1892013 | 0.71 | POLB (0.49) | ALDH1A1MAPK1CYP3A4CYP2C19POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012151576-A1 | METHODS OF TREATING COMPLICATIONS AND DISORDERS ASSOCIATED WITH G-CSF ADMINISTRATION | SACKSTEIN ROBERT (US) | 2012-11-08 | — | — | WO | disclosed |