Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | NSD2 | O96028 | 1/20 | 0.35 |
| ▸ | CASP6 | P55212 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | PIM1 | P11309 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.33 |
| ▸ | PPARG | P37231 | 2/20 | 0.33 |
| ▸ | NCOA2 | Q15596 | 2/20 | 0.33 |
| ▸ | NCOA1 | Q15788 | 2/20 | 0.33 |
| ▸ | NCOA3 | Q9Y6Q9 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7326384 | 0.84 | MAPT (0.43) | XDHMAPTALDH1A1TDP1PIM1 | |
| SCHEMBL13728720 | 0.75 | XDH (0.43) | XDHALDH1A1PKMKMT2APOLB | |
| SCHEMBL6265336 | 0.72 | PNP (0.58) | MAPTKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL5183529 | 0.71 | XDH (0.42) | XDHMAPTGAAKDM4EALDH1A1 | |
| SCHEMBL8700368 | 0.70 | MAPT (0.42) | XDHMAPTKDM4EALDH1A1TDP1 | |
| SCHEMBL4014478 | 0.68 | MAPT (0.40) | XDHMAPTALDH1A1 | |
| SCHEMBL9721482 | 0.67 | CYP2C19 (0.41) | XDHMAPTALDH1A1TDP1POLB | |
| SCHEMBL24559208 | 0.66 | USP2 (0.44) | XDHGAAALDH1A1PKMMEN1 | |
| SCHEMBL159446 | 0.65 | MAPT (0.68) | XDHMAPTGAAKDM4EALDH1A1 | |
| SCHEMBL22522023 | 0.65 | XDH (0.42) | XDHGAAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0485495-A1 | USE OF XANTHINE-DERIVATIVES AS INHIBITORS OF INDUCED BLOOD EOSINOPHILIA | Beecham Group p.l.c. (GB) | 1992-05-20 | — | — | EP | disclosed |
| WO-1991001730-A2 | USE OF XANTHINE-DERIVATIVES AS INHIBITORS OF INDUCED BLOOD EOSINOPHILIA | BEECHAM GROUP PLC (GB) | 1991-02-21 | — | — | WO | disclosed |