Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.75 |
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.72 |
| ▸ | HPGD | P15428 | 4/20 | 0.72 |
| ▸ | MEN1 | O00255 | 2/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.72 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.72 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.70 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.70 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.70 |
| ▸ | PPARG | P37231 | 1/20 | 0.68 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.68 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.68 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.67 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.67 |
| ▸ | GFER | P55789 | 1/20 | 0.65 |
| ▸ | POLB | P06746 | 1/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.65 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | ATM | Q13315 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7072642 | 0.90 | ALDH1A1 (0.81) | ALDH1A1HPGDMEN1KMT2AKDM4E | |
| SCHEMBL15452371 | 0.84 | TDP1 (0.76) | TDP1ALDH1A1HPGDKDM4EMAPK10 | |
| SCHEMBL15452785 | 0.83 | ALDH1A1 (0.74) | TDP1ALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL5429664 | 0.83 | ALDH1A1 (0.75) | ALDH1A1HPGDMEN1KMT2AKDM4E | |
| SCHEMBL8978517 | 0.83 | ALDH1A1 (0.75) | ALDH1A1HPGDMEN1KMT2AKDM4E | |
| SCHEMBL8978542 | 0.82 | ALDH1A1 (0.69) | TDP1ALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL28538869 | 0.82 | HPGD (0.77) | TDP1ALDH1A1HPGDKDM4EMAPK10 | |
| SCHEMBL13196160 | 0.81 | TDP1 (0.70) | TDP1ALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL8978622 | 0.80 | HPGD (0.79) | ALDH1A1HPGDMEN1KMT2AKDM4E | |
| SCHEMBL20869730 | 0.80 | ALDH1A1 (0.73) | TDP1ALDH1A1HPGDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160354375-A1 | CASEIN KINASE 1delta (CK 1delta) INHIBITORS AND THEIR USE IN THE TREATMENT OF NEURODEGENERATIVE DISEASES SUCH AS TAUOPATHIES | ELECTROPHORETICS LIMITED (GB) | 2016-12-08 | — | — | US | disclosed |
| US-8829016-B2 | Triazole compounds as potential anti-inflammatory agents | KING SAUD UNIVERSITY (SA) | 2014-09-09 | — | — | US | disclosed |
| US-8829016-B2 | Triazole compounds as potential anti-inflammatory agents | KING SAUD UNIVERSITY (SA) | 2014-09-09 | — | — | US | disclosed |
| US-20140045902-A1 | NEW TRIAZOLE COMPOUNDS AS POTENTIAL ANTI-INFLAMMATORY AGENTS | KING SAUD UNIVERSITY (SA) | 2014-02-13 | — | — | US | disclosed |
| US-20140045902-A1 | NEW TRIAZOLE COMPOUNDS AS POTENTIAL ANTI-INFLAMMATORY AGENTS | KING SAUD UNIVERSITY (SA) | 2014-02-13 | — | — | US | disclosed |
| EP-2527335-B1 | Triazole compounds as anti-inflammatory agents | UNIV KING SAUD (SA) | 2013-09-18 | — | — | EP | disclosed |
| EP-2527335-B1 | Triazole compounds as anti-inflammatory agents | UNIV KING SAUD (SA) | 2013-09-18 | — | — | EP | disclosed |
| WO-2012146362-A1 | TRIAZOLE COMPOUNDS AS POTENTIAL ANTI-INFLAMMATORY AGENTS | KING SAUD UNIVERSITY (SA) | 2012-11-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140045902-A1 | NEW TRIAZOLE COMPOUNDS AS POTENTIAL ANTI-INFLAMMATORY AGENTS | PTGER2, PTGER1, PTGER3 | TDP1 3286/4885ALDH1A1 565/4885HPGD 399/4885 |
| US-20160354375-A1 | CASEIN KINASE 1delta (CK 1delta) INHIBITORS AND THEIR USE IN THE TREATMENT OF NEURODEGENERATIVE DISEASES SUCH AS TAUOPATHIES | CSNK1G1, CSNK1A1, CSNK1D | TDP1 392/4885ALDH1A1 2638/4885HPGD 3887/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.