Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.77 |
| ▸ | HTT | P42858 | 1/20 | 0.77 |
| ▸ | CUL4A | Q13619 | 1/20 | 0.77 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.76 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.67 |
| ▸ | POLB | P06746 | 1/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.67 |
| ▸ | CA1 | P00915 | 2/20 | 0.65 |
| ▸ | CA2 | P00918 | 2/20 | 0.65 |
| ▸ | CA12 | O43570 | 1/20 | 0.65 |
| ▸ | CA9 | Q16790 | 1/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.64 |
| ▸ | GAA | P10253 | 1/20 | 0.64 |
| ▸ | RECQL | P46063 | 1/20 | 0.64 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.64 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.64 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7691829 | 0.91 | HPGD (0.91) | HPGDHTTCUL4ATDP1ALDH1A1 | |
| SCHEMBL8978622 | 0.84 | HPGD (0.79) | HPGDHTTCUL4AALDH1A1CA1 | |
| SCHEMBL28543630 | 0.84 | KDM4E (0.79) | HPGDHTTCUL4ATDP1ALDH1A1 | |
| SCHEMBL15452371 | 0.82 | TDP1 (0.76) | HPGDHTTTDP1ALDH1A1POLB | |
| SCHEMBL13729062 | 0.82 | TDP1 (0.75) | HPGDHTTTDP1ALDH1A1POLB | |
| SCHEMBL28537279 | 0.79 | KDM4E (1.00) | HPGDHTTCUL4ATDP1ALDH1A1 | |
| SCHEMBL7686805 | 0.77 | CHRNE (0.73) | HPGDHTTCUL4AALDH1A1POLB | |
| SCHEMBL28911095 | 0.77 | KDM4E (0.71) | HPGDHTTCUL4ATDP1ALDH1A1 | |
| SCHEMBL11920079 | 0.75 | OXTR (0.52) | HPGDHTTCUL4AL3MBTL1CYP3A4 | |
| SCHEMBL8931026 | 0.75 | KDM4E (0.85) | HPGDHTTCUL4AALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112358466-B | 1,2, 4-triazole-norfloxacin heterozygote and preparation method and application thereof | 广东省微生物研究所（广东省微生物分析检测中心） | 2021-10-26 | — | — | CN | disclosed |
| CN-112358466-A | 1,2, 4-triazole-norfloxacin heterozygote and preparation method and application thereof | 广东省微生物研究所（广东省微生物分析检测中心） | 2021-02-12 | — | — | CN | disclosed |