Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 20/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.43 |
| ▸ | DPP7 | Q9UHL4 | 5/20 | 0.43 |
| ▸ | DPP8 | Q6V1X1 | 5/20 | 0.43 |
| ▸ | DPP9 | Q86TI2 | 3/20 | 0.43 |
| ▸ | ACE | P12821 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | FAP | Q12884 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14550112 | 0.85 | DPP4 (0.60) | DPP4DPP7HTR2A | |
| SCHEMBL3144411 | 0.85 | DPP4 (0.60) | DPP4DPP7HTR2A | |
| Adipic Acid SCHEMBL13729710 | 0.84 | DPP4 (0.45) | DPP4CYP3A4DPP7DPP8DPP9 | |
| Hydrochloric Acid SCHEMBL13730062 | 0.84 | DPP4 (0.58) | DPP4DPP7HTR2A | |
| Phosphoric Acid SCHEMBL13730837 | 0.83 | DPP4 (0.50) | DPP4CYP3A4DPP7DPP8DPP9 | |
| Phosphoric Acid SCHEMBL14128618 | 0.81 | DPP4 (0.49) | DPP4CYP3A4DPP7DPP8DPP9 | |
| SCHEMBL13729579 | 0.76 | DPP4 (0.47) | DPP4CYP3A4DPP7DPP8DPP9 | |
| Gentisic Acid SCHEMBL13732886 | 0.76 | CA12 (0.49) | DPP4CYP3A4DPP7DPP8DPP9 | |
| Trifluoroacetic Acid SCHEMBL3134971 | 0.76 | DPP4 (0.42) | DPP4CYP3A4DPP7DPP8DPP9 | |
| SCHEMBL29441819 | 0.76 | DPP4 (0.55) | DPP4CYP3A4DPP7DPP8DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2681220-A2 | NOVEL SALTS OF DPP-IV INHIBITOR | Cadila Healthcare Limited (IN) | 2014-01-08 | — | — | EP | claimed |
| WO-2012147092-A2 | NOVEL SALTS OF DPP-IV INHIBITOR | CADILA HEALTHCARE LIMITED (IN) | 2012-11-01 | — | — | WO | claimed |
| EP-2681220-A2 | NOVEL SALTS OF DPP-IV INHIBITOR | Cadila Healthcare Limited (IN) | 2014-01-08 | — | — | EP | disclosed |
| WO-2012147092-A2 | NOVEL SALTS OF DPP-IV INHIBITOR | CADILA HEALTHCARE LIMITED (IN) | 2012-11-01 | — | — | WO | disclosed |