Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 known ✓ | P27487 | 20/20 | 0.50 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.43 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.42 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphoric Acid SCHEMBL14128618 | 0.98 | DPP4 (0.49) | DPP4DPP7DPP8DPP9CYP3A4 | |
| SCHEMBL3144411 | 0.89 | DPP4 (0.60) | DPP4DPP7 | |
| SCHEMBL14550112 | 0.89 | DPP4 (0.60) | DPP4DPP7 | |
| Hydrochloric Acid SCHEMBL13730062 | 0.88 | DPP4 (0.58) | DPP4DPP7 | |
| Trifluoroacetic Acid SCHEMBL13729613 | 0.83 | DPP4 (0.49) | DPP4DPP7DPP8DPP9CYP3A4 | |
| Adipic Acid SCHEMBL13729710 | 0.81 | DPP4 (0.45) | DPP4DPP7DPP8DPP9CYP3A4 | |
| SCHEMBL13729579 | 0.77 | DPP4 (0.47) | DPP4DPP7DPP8DPP9CYP3A4 | |
| SCHEMBL16750214 | 0.75 | DPP4 (0.58) | DPP4DPP7DPP8CYP3A4 | |
| SCHEMBL13780809 | 0.75 | DPP4 (0.58) | DPP4DPP7DPP8CYP3A4 | |
| Gentisic Acid SCHEMBL13732886 | 0.74 | CA12 (0.49) | DPP4DPP7DPP8DPP9CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2681220-A2 | NOVEL SALTS OF DPP-IV INHIBITOR | Cadila Healthcare Limited (IN) | 2014-01-08 | — | — | EP | disclosed |
| WO-2012147092-A2 | NOVEL SALTS OF DPP-IV INHIBITOR | CADILA HEALTHCARE LIMITED (IN) | 2012-11-01 | — | — | WO | disclosed |