Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 13/20 | 0.42 |
| ▸ | DPP7 | Q9UHL4 | 6/20 | 0.38 |
| ▸ | DPP9 | Q86TI2 | 5/20 | 0.38 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.36 |
| ▸ | FAP | Q12884 | 2/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.35 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.35 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | GABRP | O00591 | 2/20 | 0.34 |
| ▸ | GABRD | O14764 | 2/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.34 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4697922 | 0.85 | DPP4 (0.55) | DPP4DPP7DPP9DPP8FAP | |
| Adipic Acid SCHEMBL13729711 | 0.84 | GABRP (0.44) | DPP4DPP7DPP9DPP8FAP | |
| Hydrochloric Acid SCHEMBL13730064 | 0.84 | DPP4 (0.53) | DPP4DPP7DPP9DPP8FAP | |
| Phosphoric Acid SCHEMBL13730179 | 0.83 | DPP4 (0.46) | DPP4DPP7DPP9DPP8FAP | |
| Phosphoric Acid SCHEMBL14128619 | 0.81 | DPP4 (0.45) | DPP4DPP7DPP9DPP8FAP | |
| SCHEMBL15155703 | 0.77 | GABRR1 (0.45) | DPP4HDAC1HDAC8 | |
| Gentisic Acid SCHEMBL13729892 | 0.76 | CA1 (0.49) | CYP3A4 | |
| Trifluoroacetic Acid SCHEMBL13729613 | 0.76 | DPP4 (0.49) | DPP4DPP7DPP9DPP8FAP | |
| SCHEMBL25186554 | 0.76 | USP2 (0.43) | DPP4DPP7DPP9DPP8FAP | |
| SCHEMBL3717133 | 0.76 | USP2 (0.43) | DPP4DPP7DPP9DPP8FAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2681220-A2 | NOVEL SALTS OF DPP-IV INHIBITOR | Cadila Healthcare Limited (IN) | 2014-01-08 | — | — | EP | claimed |
| WO-2012147092-A2 | NOVEL SALTS OF DPP-IV INHIBITOR | CADILA HEALTHCARE LIMITED (IN) | 2012-11-01 | — | — | WO | claimed |
| EP-2205083-A1 | SUBSTITUTED ARYL SULFONE DERIVATIVES AS CALCIUM CHANNEL BLOCKERS | Merck Sharp & Dohme Corp. (US) | 2010-07-14 | — | — | EP | claimed |
| WO-2009045382-A1 | SUBSTITUTED ARYL SULFONE DERIVATIVES AS CALCIUM CHANNEL BLOCKERS | MERCK & CO., INC. (US) | 2009-04-09 | — | — | WO | claimed |
| EP-2681220-A2 | NOVEL SALTS OF DPP-IV INHIBITOR | Cadila Healthcare Limited (IN) | 2014-01-08 | — | — | EP | disclosed |
| WO-2012147092-A2 | NOVEL SALTS OF DPP-IV INHIBITOR | CADILA HEALTHCARE LIMITED (IN) | 2012-11-01 | — | — | WO | disclosed |