Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.35 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.34 |
| ▸ | GBA1 | P04062 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13729778 | 0.74 | ALDH1A1 (0.35) | ALDH1A1POLBSMN1; SMN2LMNACASP1 | |
| SCHEMBL25689654 | 0.68 | ALDH1A1 (0.66) | ALDH1A1POLBSMN1; SMN2LMNACASP1 | |
| SCHEMBL9946220 | 0.66 | KDM4E (0.64) | ALDH1A1LMNAMEN1KMT2ANPC1 | |
| SCHEMBL3187881 | 0.66 | KDM4E (0.31) | ALDH1A1POLBMEN1KMT2AMAPT | |
| SCHEMBL4820737 | 0.65 | ALDH1A1 (0.97) | ALDH1A1POLBSMN1; SMN2LMNACASP1 | |
| SCHEMBL4812899 | 0.65 | ALDH1A1 (0.97) | ALDH1A1POLBSMN1; SMN2LMNACASP1 | |
| SCHEMBL25689688 | 0.64 | ALDH1A1 (0.63) | ALDH1A1POLBSMN1; SMN2LMNAMEN1 | |
| SCHEMBL30708890 | 0.61 | NR1H2 (0.53) | ALDH1A1POLBSMN1; SMN2MAPTKDM4E | |
| SCHEMBL26969841 | 0.61 | NR1H2 (0.53) | ALDH1A1POLBSMN1; SMN2MAPTKDM4E | |
| SCHEMBL27903086 | 0.61 | GBA1 (0.43) | ALDH1A1POLBSMN1; SMN2LMNACASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012151567-A1 | PYRIMIDINONE COMPOUNDS AND METHODS FOR PREVENTING AND TREATING INFLUENZA | ST. JUDE CHILDREN'S RESEARCH HOSPITAL (US) | 2012-11-08 | — | — | WO | disclosed |