Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 4/20 | 0.32 |
| ▸ | MAPT | P10636 | 4/20 | 0.32 |
| ▸ | HPGD | P15428 | 3/20 | 0.32 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13729773 | 0.74 | ALDH1A1 (0.49) | ALDH1A1RAB9AMAPTMEN1KMT2A | |
| SCHEMBL13729776 | 0.67 | HSD17B10 (0.36) | ALDH1A1L3MBTL1MAPK10LMNA | |
| SCHEMBL28119309 | 0.66 | ALDH1A1 (0.36) | ALDH1A1GAARAB9AMAPTHPGD | |
| SCHEMBL3187900 | 0.66 | MAPT (0.33) | ALDH1A1RAB9AMAPTHPGDMEN1 | |
| SCHEMBL4794241 | 0.64 | ACACB (0.41) | ALDH1A1HPGD | |
| SCHEMBL14554003 | 0.63 | SORD (0.54) | — | |
| SCHEMBL30039813 | 0.62 | MEN1 (0.54) | ALDH1A1L3MBTL1GAAMAPTMEN1 | |
| SCHEMBL3187881 | 0.60 | KDM4E (0.31) | ALDH1A1L3MBTL1GAARAB9AMAPT | |
| SCHEMBL31324954 | 0.59 | GABRP (0.42) | ALDH1A1L3MBTL1GABRG2GABRB3GABRA5 | |
| SCHEMBL441304 | 0.59 | TP53 (0.44) | L3MBTL1RAB9AMAPTHCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012151567-A1 | PYRIMIDINONE COMPOUNDS AND METHODS FOR PREVENTING AND TREATING INFLUENZA | ST. JUDE CHILDREN'S RESEARCH HOSPITAL (US) | 2012-11-08 | — | — | WO | disclosed |