Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | BCL6 | P41182 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | SYK | P43405 | 5/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | IDH2 | P48735 | 2/20 | 0.41 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.40 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17077800 | 0.78 | SYK (0.46) | MAPTALDH1A1KDM4ESYKHTT | |
| SCHEMBL22093021 | 0.77 | MAPK8 (0.51) | SYKLMNA | |
| SCHEMBL12984259 | 0.76 | DHODH (0.53) | MAPTALDH1A1KMT2AMEN1GFER | |
| SCHEMBL2528881 | 0.76 | SYK (0.43) | MAPTALDH1A1KMT2AKDM4EMEN1 | |
| SCHEMBL30721208 | 0.76 | DHODH (0.53) | MAPTALDH1A1KMT2AMEN1GFER | |
| SCHEMBL10280708 | 0.75 | MAT2A (0.40) | MAPTALDH1A1KMT2AL3MBTL1KDM4E | |
| SCHEMBL13730151 | 0.75 | GSK3B (0.56) | MAPTALDH1A1KMT2AL3MBTL1MEN1 | |
| SCHEMBL14604480 | 0.75 | TRPV1 (0.44) | KMT2AL3MBTL1MEN1SYKCYP3A4 | |
| SCHEMBL30069224 | 0.74 | BCL6 (0.49) | MAPTALDH1A1KMT2AL3MBTL1BCL6 | |
| SCHEMBL849309 | 0.74 | SYK (0.44) | MAPTALDH1A1KMT2AKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012146667-A1 | IMIDAZOPYRIDINE DERIVATIVES AS PI3K INHIBITORS | ALMIRALL, S.A. (ES) | 2012-11-01 | — | — | WO | disclosed |