Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL6 | P41182 | 2/20 | 0.53 |
| ▸ | EGFR | P00533 | 8/20 | 0.48 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7687919 | 0.83 | AURKA (0.49) | EGFRGAAALDH1A1TDP1HTT | |
| SCHEMBL18338088 | 0.82 | KMT2A (0.54) | BCL6EGFRGAAALDH1A1TDP1 | |
| SCHEMBL6384523 | 0.82 | EGFR (0.38) | BCL6EGFRHTTABL1ABL2 | |
| SCHEMBL4902552 | 0.81 | RAB9A (0.51) | EGFRGAAALDH1A1HTTMAPT | |
| SCHEMBL10138755 | 0.79 | IGF1R (0.46) | BCL6EGFRGAAALDH1A1TDP1 | |
| SCHEMBL6564572 | 0.79 | BCL6 (0.45) | BCL6EGFRKDM4ECYP3A4PIN1 | |
| SCHEMBL19432441 | 0.79 | MAPT (0.50) | BCL6EGFRGAAALDH1A1TDP1 | |
| SCHEMBL18434110 | 0.79 | SYK (0.50) | BCL6EGFRABL1JAK2LRRK2 | |
| SCHEMBL13506355 | 0.79 | BCL6 (0.57) | BCL6EGFRGAAALDH1A1TDP1 | |
| SCHEMBL1624893 | 0.77 | MAPKAPK2 (0.44) | ABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012146667-A1 | IMIDAZOPYRIDINE DERIVATIVES AS PI3K INHIBITORS | ALMIRALL, S.A. (ES) | 2012-11-01 | — | — | WO | disclosed |