Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL6 | P41182 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | S100A9 | P06702 | 2/20 | 0.42 |
| ▸ | EGFR | P00533 | 2/20 | 0.41 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.41 |
| ▸ | DHODH | Q02127 | 2/20 | 0.41 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.40 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.40 |
| ▸ | JAK2 | O60674 | 2/20 | 0.40 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.40 |
| ▸ | IGF1R | P08069 | 2/20 | 0.39 |
| ▸ | PLK4 | O00444 | 1/20 | 0.39 |
| ▸ | AURKA | O14965 | 1/20 | 0.39 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.39 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.39 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.39 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.39 |
| ▸ | INSR | P06213 | 1/20 | 0.39 |
| ▸ | LCK | P06239 | 1/20 | 0.39 |
| ▸ | FYN | P06241 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18338088 | 0.82 | KMT2A (0.54) | BCL6EGFRJAK2LRRK2MAP4K4 | |
| SCHEMBL13730481 | 0.79 | BCL6 (0.53) | BCL6KDM4EEGFRPIN1JAK2 | |
| SCHEMBL18434110 | 0.79 | SYK (0.50) | BCL6EGFRDHODHJAK2LRRK2 | |
| SCHEMBL15635744 | 0.79 | DHODH (0.64) | KDM4EDHODHCYP3A4 | |
| SCHEMBL16684787 | 0.72 | PIN1 (0.57) | BCL6KDM4ES100A9EGFRPIN1 | |
| SCHEMBL21377511 | 0.72 | S100A9 (0.47) | KDM4ES100A9 | |
| SCHEMBL11971210 | 0.71 | DHODH (0.61) | KDM4EDHODH | |
| SCHEMBL6525797 | 0.70 | ABCG2 (0.50) | BCL6KDM4ECYP3A4 | |
| SCHEMBL7687919 | 0.70 | AURKA (0.49) | EGFRALKAURKAPRKD3MAP4K4 | |
| SCHEMBL18434184 | 0.70 | MAPT (0.55) | BCL6KDM4EJAK2LRRK2IGF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1304994-B1 | PYRROLYL-SUBSTITUTED NITROPHENOLS USED AS DIRECT COLORANTS | HENKEL KGAA (DE) | 2004-10-20 | — | — | EP | disclosed |