Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | TET2 | Q6N021 | 3/20 | 0.32 |
| ▸ | KDM4A | O75164 | 2/20 | 0.32 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.32 |
| ▸ | KDM2A | Q9Y2K7 | 2/20 | 0.32 |
| ▸ | TET3 | O43151 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethylene Glycol SCHEMBL15655041 | 0.82 | OR51E2 (0.52) | OR51E2GPR84FFAR1SMN1; SMN2TET2 | |
| Malic Acid SCHEMBL1131217 | 0.82 | SMN1; SMN2 (0.60) | MAPTOR51E2SMN1; SMN2TET2KDM4A | |
| Cadaverine Tartrate SCHEMBL1131805 | 0.80 | MAPT (0.57) | MAPTOR51E2 | |
| Lactic Acid SCHEMBL1131790 | 0.80 | MAPT (0.57) | MAPTOR51E2 | |
| Cadaverine Tartrate SCHEMBL989096 | 0.80 | MAPT (0.57) | MAPTOR51E2 | |
| Tartaric Acid SCHEMBL30104959 | 0.80 | MAPT (0.57) | MAPTOR51E2 | |
| Alcohol SCHEMBL28323398 | 0.79 | OR51E2 (0.55) | OR51E2GPR84FFAR1SMN1; SMN2TET2 | |
| SCHEMBL193026 | 0.79 | — | — | |
| SCHEMBL15355768 | 0.79 | — | — | |
| SCHEMBL264859 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2702136-B1 | METHOD FOR LYSING CELLS | MERCK PATENT GMBH (DE) | 2017-10-25 | — | — | EP | disclosed |
| US-9493736-B2 | Method for lysing cells | MERCK PATENT GMBH (DE) | 2016-11-15 | — | — | US | disclosed |
| EP-2702136-A1 | METHOD FOR LYSING CELLS | Merck Patent GmbH (DE) | 2014-03-05 | — | — | EP | disclosed |
| US-20140051088-A1 | METHOD FOR LYSING CELLS | MERCK PATENT GMBH (DE) | 2014-02-20 | — | — | US | disclosed |
| WO-2012146338-A1 | METHOD FOR LYSING CELLS | MERCK PATENT GMBH (DE) | 2012-11-01 | — | — | WO | disclosed |