Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 8/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29459542 | 0.78 | HIF1A (0.41) | HIF1APTGS2ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL29360626 | 0.78 | HIF1A (0.41) | HIF1APTGS2ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL19855 | 0.78 | HIF1A (0.41) | HIF1APTGS2ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL1274291 | 0.78 | HIF1A (0.41) | HIF1APTGS2ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL120673 | 0.78 | HIF1A (0.41) | HIF1APTGS2ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL16736989 | 0.78 | HIF1A (0.41) | HIF1APTGS2ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL29363117 | 0.78 | HIF1A (0.41) | HIF1APTGS2ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL19206930 | 0.78 | HIF1A (0.41) | HIF1APTGS2ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL120674 | 0.78 | HIF1A (0.41) | HIF1APTGS2ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL30086156 | 0.78 | HIF1A (0.41) | HIF1APTGS2ALDH1A1HPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2699093-A1 | ACTIVE COMPOUND COMBINATIONS COMPRISING A (THIO)CARBOXAMIDE DERIVATIVE AND A FUNGICIDAL COMPOUND | Bayer Intellectual Property GmbH (DE) | 2014-02-26 | — | — | EP | claimed |
| WO-2012143127-A1 | ACTIVE COMPOUND COMBINATIONS COMPRISING A (THIO)CARBOXAMIDE DERIVATIVE AND A FUNGICIDAL COMPOUND | BAYER CROPSCIENCES AG (DE) | 2012-10-26 | — | — | WO | claimed |