SCHEMBL120674

SCHEMBL120674

CNC(=O)C(=NOC)c1ccccc1CON=C(C)/C=C/c1c(Cl)cccc1Cl

nearest known ligand 0.41

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 8/20 0.41
PTGS2 P35354 1/20 0.39
HPGD P15428 3/20 0.38
GLA P06280 1/20 0.38
KMT2A Q03164 3/20 0.38
MEN1 O00255 2/20 0.38
NPC1 O15118 1/20 0.38
ALDH1A1 P00352 1/20 0.38
CASP3 P42574 1/20 0.38
RAB9A P51151 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
SENP7 Q9BQF6 1/20 0.38
POLB P06746 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30086156 1.00 HIF1A (0.41) HIF1APTGS2HPGDGLAKMT2A
SCHEMBL29363117 1.00 HIF1A (0.41) HIF1APTGS2HPGDGLAKMT2A
SCHEMBL29459542 1.00 HIF1A (0.41) HIF1APTGS2HPGDGLAKMT2A
SCHEMBL29360626 1.00 HIF1A (0.41) HIF1APTGS2HPGDGLAKMT2A
SCHEMBL1274291 1.00 HIF1A (0.41) HIF1APTGS2HPGDGLAKMT2A
SCHEMBL120673 1.00 HIF1A (0.41) HIF1APTGS2HPGDGLAKMT2A
SCHEMBL16736989 1.00 HIF1A (0.41) HIF1APTGS2HPGDGLAKMT2A
SCHEMBL19206930 1.00 HIF1A (0.41) HIF1APTGS2HPGDGLAKMT2A
SCHEMBL19855 1.00 HIF1A (0.41) HIF1APTGS2HPGDGLAKMT2A
SCHEMBL29355881 1.00 HIF1A (0.41) HIF1APTGS2HPGDGLAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 822 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3010893-B1 ARYLSULFIDE AND ARYLSULFOXIDE DERIVATIVES AS ACARICIDES AND INSECTICIDES BAYER CROPSCIENCE AG (DE) 2019-10-02 EP claimed
EP-3010889-B1 ARYLSULFIDE AND ARYLSULFOXIDE DERIVATIVES AS ACARICIDES AND INSECTICIDES BAYER CROPSCIENCE AG (DE) 2018-10-03 EP claimed
EP-2793578-B1 N-ARYLAMIDINE-SUBSTITUTED TRIFLUOROETHYLSULFIDE DERIVATIVES AS ACARICIDES AND INSECTICIDES BAYER CROPSCIENCE AG (DE) 2018-06-06 EP claimed
US-20180103640-A1 PROCESS FOR IMPROVING SEEDLING GROWTH AND/OR EARLY EMERGENCE OF CROPS BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2018-04-19 US claimed
US-20170265470-A1 Anthranilamides in combination with fungicides BAYER INTELLECTUAL PROPERTY GMBH (DE) 2017-09-21 US claimed
US-9642363-B2 N-arylamidine-substituted trifluoroethyl sulfide derivatives as acaricides and insecticides BAYER CROPSCIENCE AG (DE) 2017-05-09 US claimed
US-20160145235-A1 ARYL SULFIDE DERIVATIVES AND ARYL SULFOXIDE DERIVATIVES AS ACARICIDES AND INSECTICIDES BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2016-05-26 US claimed
US-20160128331-A1 ANTHRANILAMIDES IN COMBINATION WITH FUNGICIDES BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2016-05-12 US claimed
US-20160130240-A1 ARYL SULFIDE DERIVATIVES AND ARYL SULFOXIDE DERIVATIVES AS ACARICIDES AND INSECTICIDES BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2016-05-12 US claimed
EP-2997825-A1 ACTIVE COMPOUND COMBINATIONS COMPRISING A (THIO)CARBOXAMIDE DERIVATIVE AND A FUNGICIDAL COMPOUND Bayer Intellectual Property GmbH (DE) 2016-03-23 EP claimed
US-20110124501-A1 Active compound combinations BAYER CROPSCIENCE AG (DE) 2011-05-26 US claimed
US-20110064827-A1 Active compound combinations BAYER CROPSCIENCE AG (DE) 2011-03-17 US claimed
US-20110052555-A1 PESTICIDE COMPOSITION COMPRISING A TETRAZOLYLOXIME DERIVATIVE AND A FUNGICIDE OR AN INSECTICIDE ACTIVE SUBSTANCE BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2011-03-03 US claimed
US-20110033433-A1 Combinations of Fungicidally Active Yeast and Fungicides BAYER CROPSCIENCE AG (DE) 2011-02-10 US claimed
US-20110009267-A1 Process for Improving Seedling Growth and/or Early Emergence of Crops BAYER CROPSCIENCE AG (DE) 2011-01-13 US claimed
WO-2011003533-A2 PROCESS FOR IMPROVING SEEDLING GROWTH AND/OR EARLY EMERGENCE OF CROPS BAYER CROPSCIENCE AG (DE) 2011-01-13 WO claimed
EP-2272345-A1 Process for improving seedling growth and/or early emergence of crops Bayer CropScience AG (DE) 2011-01-12 EP claimed
EP-2269454-A1 Combinations of fungicidally active yeast and fungicides Bayer CropScience AG (DE) 2011-01-05 EP claimed
WO-2010149369-A1 COMBINATIONS OF FUNGICIDALLY ACTIVE YEAST AND FUNGICIDES BAYER CROPSCIENCE AG (DE) 2010-12-29 WO claimed
WO-2010094728-A1 PESTICIDE COMPOSITION COMPRISING A TETRAZOLYLOXIME DERIVATIVE AND A FUNGICIDE OR AN INSECTICIDE ACTIVE SUBSTANCE BAYER CROPSCIENCE AG (DE) 2010-08-26 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110064827-A1 Active compound combinations TST, DPM1, DDT HIF1A 3895/4885PTGS2 2130/4885HPGD 2768/4885
US-20110124501-A1 Active compound combinations CYP51A1, CA4, BROX HIF1A 2374/4885PTGS2 2691/4885HPGD 2474/4885
US-20180103640-A1 PROCESS FOR IMPROVING SEEDLING GROWTH AND/OR EARLY EMERGENCE OF CROPS EEF1A1, BTF3, EEF1A2 HIF1A 1481/4885PTGS2 1029/4885HPGD 2622/4885
US-20160130240-A1 ARYL SULFIDE DERIVATIVES AND ARYL SULFOXIDE DERIVATIVES AS ACARICIDES AND INSECTICIDES ARSA, SQOR, AHR HIF1A 4557/4885PTGS2 1893/4885HPGD 2739/4885
US-20110009267-A1 Process for Improving Seedling Growth and/or Early Emergence of Crops EEF1A1, BTF3, EEF1A2 HIF1A 1481/4885PTGS2 1029/4885HPGD 2622/4885
US-20110052555-A1 PESTICIDE COMPOSITION COMPRISING A TETRAZOLYLOXIME DERIVATIVE AND A FUNGICIDE OR AN INSECTICIDE ACTIVE SUBSTANCE DDT, TH, PRDX5 HIF1A 4692/4885PTGS2 2882/4885HPGD 4153/4885
US-20160145235-A1 ARYL SULFIDE DERIVATIVES AND ARYL SULFOXIDE DERIVATIVES AS ACARICIDES AND INSECTICIDES ARSA, SQOR, AHR HIF1A 4452/4885PTGS2 2072/4885HPGD 2758/4885
US-20160128331-A1 ANTHRANILAMIDES IN COMBINATION WITH FUNGICIDES AADAC, ANTXR2, CYP51A1 HIF1A 3943/4885PTGS2 3083/4885HPGD 3283/4885
US-20170265470-A1 Anthranilamides in combination with fungicides AADAC, ANTXR2, CYP51A1 HIF1A 3943/4885PTGS2 3083/4885HPGD 3283/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.