SCHEMBL19206930

SCHEMBL19206930

CNC(=O)/C(=N/OC)c1ccccc1CON=C(C)/C=C/c1c(Cl)cccc1Cl

nearest known ligand 0.41

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 8/20 0.41
PTGS2 P35354 1/20 0.39
HPGD P15428 3/20 0.38
GLA P06280 1/20 0.38
KMT2A Q03164 3/20 0.38
MEN1 O00255 2/20 0.38
NPC1 O15118 1/20 0.38
ALDH1A1 P00352 1/20 0.38
CASP3 P42574 1/20 0.38
RAB9A P51151 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
SENP7 Q9BQF6 1/20 0.38
POLB P06746 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30086156 1.00 HIF1A (0.41) HIF1APTGS2HPGDGLAKMT2A
SCHEMBL29363117 1.00 HIF1A (0.41) HIF1APTGS2HPGDGLAKMT2A
SCHEMBL29459542 1.00 HIF1A (0.41) HIF1APTGS2HPGDGLAKMT2A
SCHEMBL29360626 1.00 HIF1A (0.41) HIF1APTGS2HPGDGLAKMT2A
SCHEMBL1274291 1.00 HIF1A (0.41) HIF1APTGS2HPGDGLAKMT2A
SCHEMBL120673 1.00 HIF1A (0.41) HIF1APTGS2HPGDGLAKMT2A
SCHEMBL16736989 1.00 HIF1A (0.41) HIF1APTGS2HPGDGLAKMT2A
SCHEMBL120674 1.00 HIF1A (0.41) HIF1APTGS2HPGDGLAKMT2A
SCHEMBL19855 1.00 HIF1A (0.41) HIF1APTGS2HPGDGLAKMT2A
SCHEMBL29355881 1.00 HIF1A (0.41) HIF1APTGS2HPGDGLAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3010893-B1 ARYLSULFIDE AND ARYLSULFOXIDE DERIVATIVES AS ACARICIDES AND INSECTICIDES BAYER CROPSCIENCE AG (DE) 2019-10-02 EP claimed
US-12102087-B2 Active compound combinations containing a thiazoylisoxazoline and a fungicide BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2024-10-01 US disclosed
EP-4384013-A1 PROTEIN AGGREGATION INHIBITING COMPOUNDS FOR PLANT DISEASE CONTROL MAX-PLANCK-GESELLSCHAFT ZUR FÖRDERUNG DER WISSENSCHAFTEN E.V. (DE) 2024-06-19 EP disclosed
WO-2023073115-A1 PROTEIN AGGREGATION INHIBITING COMPOUNDS FOR PLANT DISEASE CONTROL MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2023-05-04 WO disclosed
EP-4173485-A1 PROTEIN AGGREGATION INHIBITING COMPOUNDS FOR PLANT DISEASE CONTROL Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2023-05-03 EP disclosed
CN-114466836-A Solvates of abscisic acid and liquid compositions containing abscisic acid 科莱恩国际有限公司 2022-05-10 CN disclosed
CN-109561676-B Use of N-substituted pyrrolidones for promoting penetration of agrochemical active ingredients 科莱恩国际有限公司 2022-04-29 CN disclosed
CN-113243374-B Heterocyclic compounds as pesticides 拜耳农作物科学股份公司 2022-04-26 CN disclosed
CN-108004235-B Soybean event SYHT0H2 and compositions and methods for detection thereof 先正达参股股份有限公司 2022-02-08 CN disclosed
US-20210321615-A1 ACTIVE COMPOUND COMBINATIONS CONTAINING A THIAZOYLISOXAZOLINE AND A FUNGICIDE BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2021-10-21 US disclosed
CN-107926985-B Compositions comprising biological control agents and fungicides 拜尔农作物科学股份公司 2021-02-02 CN disclosed
CN-112188836-A Agrochemical formulations comprising polymeric crystal growth inhibitors 拜耳公司 2021-01-05 CN disclosed
CN-111741680-A Use of fungicides for controlling mottled scab in apples 拜耳公司 2020-10-02 CN disclosed
CN-106715424-B Bicyclic compounds as pesticides 拜耳作物科学股份公司 2020-07-14 CN disclosed
CN-111200933-A Active ingredient compositions comprising N-enoyl-N-alkylglucamides and their use 科莱恩国际有限公司 2020-05-26 CN disclosed
CN-106962403-B Compositions comprising biological control agents and pesticides 拜耳作物科学股份公司 2020-05-05 CN disclosed
CN-107108564-B Novel halogen substituted compounds 拜耳作物科学股份公司 2020-02-07 CN disclosed
CN-110678076-A Plant treatment products and related methods 美国赛多美科技有限公司 2020-01-10 CN disclosed
US-20190110472-A1 ACTIVE INGREDIENT COMPOSITIONS COMPRISING N-ALKENOYL-N-ALKYLGLUCAMIDES AND THE USE THEREOF CLARIANT INTERNATIONAL, LTD. (CH) 2019-04-18 US disclosed
US-20170231223-A1 Organic Ammonium Salts Of Anionic Pesticides CLARIANT INTERNATIONAL LTD. (CH) 2017-08-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190110472-A1 ACTIVE INGREDIENT COMPOSITIONS COMPRISING N-ALKENOYL-N-ALKYLGLUCAMIDES AND THE USE THEREOF B3GNT2, GANAB, GBA2 HIF1A 1924/4885PTGS2 2515/4885HPGD 2168/4885
US-12102087-B2 Active compound combinations containing a thiazoylisoxazoline and a fungicide CYP4X1, BROX, PRDX5 HIF1A 3838/4885PTGS2 3916/4885HPGD 3669/4885
US-20210321615-A1 ACTIVE COMPOUND COMBINATIONS CONTAINING A THIAZOYLISOXAZOLINE AND A FUNGICIDE CYP4X1, BROX, PRDX5 HIF1A 3838/4885PTGS2 3916/4885HPGD 3669/4885
US-20170231223-A1 Organic Ammonium Salts Of Anionic Pesticides HCN3, HCN4, KCNH3 HIF1A 4463/4885PTGS2 4172/4885HPGD 4579/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.