SCHEMBL13732129

SCHEMBL13732129

FC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)CCSC(=S)c1ccccc1

nearest known ligand 0.30

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CES1 P23141 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15403413 0.82 KMT2A (0.37) CES1
SCHEMBL630363 0.80 CES1 (0.38) CES1
SCHEMBL2433898 0.75 CES1 (0.39) CES1
SCHEMBL8484616 0.72 ALDH1A1 (0.48)
SCHEMBL15403553 0.72 KMT2A (0.36) CES1
SCHEMBL15403165 0.70 KMT2A (0.37) CES1
SCHEMBL15403099 0.69 KMT2A (0.39) CES1
SCHEMBL2430958 0.68 CES1 (0.41) CES1
SCHEMBL163065 0.68 NOS1 (0.52)
SCHEMBL7584115 0.68 MAPT (0.47) CES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012142670-A1 NUCLEAR MAGNETIC RESONANCE AGENT THE UNIVERSITY OF QUEENSLAND (AU) 2012-10-26 WO disclosed