Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 1/20 | 0.39 |
| ▸ | NOS1 | P29475 | 1/20 | 0.39 |
| ▸ | NOS2 | P35228 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 4/20 | 0.35 |
| ▸ | DHODH | Q02127 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.33 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | SYK | P43405 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17680368 | 0.86 | AR (0.32) | DHODHSMN1; SMN2MAPTABCB1ABCG2 | |
| SCHEMBL10319231 | 0.86 | DHODH (0.40) | NOS3NOS1NOS2DHODHSMN1; SMN2 | |
| SCHEMBL17666817 | 0.85 | AR (0.33) | DHODHSMN1; SMN2MAPTABCB1ABCG2 | |
| SCHEMBL17680359 | 0.85 | TLR8 (0.39) | NOS3NOS1NOS2DHODHSMN1; SMN2 | |
| SCHEMBL16362419 | 0.81 | DHODH (0.36) | NOS3NOS1NOS2DHODHSMN1; SMN2 | |
| SCHEMBL17666818 | 0.80 | CDK9 (0.35) | DHODHSMN1; SMN2MAPTKDM4EALDH1A1 | |
| SCHEMBL24513499 | 0.80 | TACR3 (0.36) | DHODHSMN1; SMN2MAPTKDM4EALDH1A1 | |
| SCHEMBL13731884 | 0.79 | GRM2 (0.35) | SMN1; SMN2MAPTABCB1ABCG2GAA | |
| SCHEMBL28865795 | 0.77 | KMT2A (0.34) | DHODHSMN1; SMN2MAPTPOLBKDM4E | |
| SCHEMBL16338555 | 0.77 | DHODH (0.38) | DHODHMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012148511-A1 | 5-SUBSTITUTED 2-PHENYLQUINOLINE COMPLEXES MATERIALS FOR LIGHT EMITTING DIODE | UNIVERSAL DISPLAY CORPORATION (US) | 2012-11-01 | — | — | WO | disclosed |