⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2868030 | 0.92 | — | — | |
| SCHEMBL21488423 | 0.82 | — | — | |
| SCHEMBL16876013 | 0.74 | — | — | |
| SCHEMBL1722705 | 0.72 | — | — | |
| SCHEMBL27224997 | 0.72 | — | — | |
| SCHEMBL2085807 | 0.71 | — | — | |
| SCHEMBL2725107 | 0.71 | TSHR (0.31) | — | |
| SCHEMBL27225038 | 0.70 | — | — | |
| SCHEMBL17363051 | 0.69 | LMNA (0.30) | — | |
| SCHEMBL1139842 | 0.69 | FFAR3 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140046059-A1 | PROCESS FOR THE PREPARATION OF MORPHOLINO SULFONYL INDOLE DERIVATIVES | Piramal Enterprises Limited (IN) | 2014-02-13 | — | — | US | disclosed |
| WO-2012143874-A1 | A PROCESS FOR THE PREPARATION OF MORPHOLINO SULFONYL INDOLE DERIVATIVES | PIRAMAL HEALTHCARE LIMITED (IN) | 2012-10-26 | — | — | WO | disclosed |