⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2725107 | 0.78 | TSHR (0.31) | — | |
| SCHEMBL27886048 | 0.77 | — | — | |
| SCHEMBL343056 | 0.75 | LMNA (0.33) | — | |
| SCHEMBL2873479 | 0.75 | LMNA (0.33) | — | |
| SCHEMBL2085807 | 0.73 | — | — | |
| SCHEMBL2498049 | 0.73 | MEN1 (0.31) | — | |
| SCHEMBL1062985 | 0.73 | LMNA (0.39) | — | |
| SCHEMBL17363051 | 0.72 | LMNA (0.30) | — | |
| SCHEMBL13732302 | 0.72 | — | — | |
| SCHEMBL1139842 | 0.71 | FFAR3 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2344449-A1 | ARYL-PHENYL-SULFONAMIDO-CYCLOALKYL COMPOUNDS AND THEIR USE | Pimco 2664 Limited (GB) | 2011-07-20 | — | — | EP | disclosed |
| WO-2010032009-A1 | ARYL-PHENYL-SULFONAMIDO-CYCLOALKYL COMPOUNDS AND THEIR USE | PIMCO 2664 LIMITED (GB) | 2010-03-25 | — | — | WO | disclosed |