Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | MAOA | P21397 | 1/20 | 0.51 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.51 |
| ▸ | CA12 | O43570 | 2/20 | 0.49 |
| ▸ | CA1 | P00915 | 2/20 | 0.49 |
| ▸ | CA2 | P00918 | 2/20 | 0.49 |
| ▸ | CA7 | P43166 | 2/20 | 0.49 |
| ▸ | CA9 | Q16790 | 2/20 | 0.49 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | SCN1A | P35498 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16098092 | 0.89 | CYP1A2 (0.51) | CYP1A2LMNACYP3A4MAOAHSD17B2 | |
| SCHEMBL2033666 | 0.84 | NOTUM (0.54) | LMNACA12CA1CA2CA7 | |
| SCHEMBL31003812 | 0.84 | NOTUM (0.54) | LMNACA12CA1CA2CA7 | |
| SCHEMBL9996771 | 0.83 | HSD17B2 (0.51) | CYP1A2LMNACYP3A4MAOAHSD17B2 | |
| SCHEMBL16528199 | 0.83 | HSD17B2 (0.51) | CYP1A2LMNACYP3A4MAOAHSD17B2 | |
| Hydrochloric Acid SCHEMBL2241815 | 0.82 | NOTUM (0.52) | LMNACA12CA1CA2CA7 | |
| SCHEMBL15670215 | 0.82 | CA12 (0.51) | CYP1A2LMNACYP3A4MAOAHSD17B2 | |
| SCHEMBL1612538 | 0.82 | HSD17B2 (0.69) | CYP1A2LMNACYP3A4MAOAHSD17B2 | |
| SCHEMBL670443 | 0.82 | CYP1A2 (0.57) | CYP1A2LMNACYP3A4MAOAHSD17B2 | |
| SCHEMBL13537289 | 0.81 | NPC1 (0.49) | CYP1A2LMNACYP3A4MAOAHSD17B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10479765-B2 | Substituted N,2-diarylquinoline-4-carboxamides and the use thereof as anti-inflammatory agents | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2019-11-19 | — | — | US | disclosed |
| US-10189788-B2 | Substituted N,2-diarylquinoline-4-carboxamides and the use thereof as anti-inflammatory agents | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2019-01-29 | — | — | US | disclosed |
| US-20190002409-A1 | SUBSTITUTED N,2-DIARYLQUINOLINE-4-CARBOXAMIDES AND THE USE THEREOF AS ANTI-INFLAMMATORY AGENTS | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2019-01-03 | — | — | US | disclosed |
| US-20170260140-A1 | SUBSTITUTED N,2-DIARYLQUINOLINE-4-CARBOXAMIDES AND THE USE THEREOF AS ANTI-INFLAMMATORY AGENTS | Bayer Pharma Aktiengesekkschaft (DE) | 2017-09-14 | — | — | US | disclosed |
| EP-3191452-A1 | SUBSTITUTED N,2-DIARYLQUINOLINE-4-CARBOXAMIDES AND THE USE THEREOF AS ANTI-INFLAMMATORY AGENTS | Bayer Pharma Aktiengesellschaft (DE) | 2017-07-19 | — | — | EP | disclosed |
| US-9555022-B2 | Substituted triazolopyridines | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2017-01-31 | — | — | US | disclosed |
| US-9555022-B2 | Substituted triazolopyridines | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2017-01-31 | — | — | US | disclosed |
| US-9555022-B2 | Substituted triazolopyridines | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2017-01-31 | — | — | US | disclosed |
| CN-103189373-B | The Triazolopyridine replaced | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2016-04-06 | — | — | CN | disclosed |
| WO-2016037954-A1 | SUBSTITUTED N,2-DIARYLQUINOLINE-4-CARBOXAMIDES AND THE USE THEREOF AS ANTI-INFLAMMATORY AGENTS | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2016-03-17 | — | — | WO | disclosed |
| US-20140120087-A1 | TRIAZOLOPYRIDINES | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-05-01 | — | — | US | disclosed |
| US-20140120087-A1 | TRIAZOLOPYRIDINES | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-05-01 | — | — | US | disclosed |
| EP-2699575-A1 | TRIAZOLOPYRIDINES | Bayer Intellectual Property GmbH (DE) | 2014-02-26 | — | — | EP | disclosed |
| CN-103608350-A | Triazolopyridine compounds | BAYER IP GMBH | 2014-02-26 | — | — | CN | disclosed |
| CN-103189373-A | Substituted triazolopyridines | BAYER IP GMBH | 2013-07-03 | — | — | CN | disclosed |
| US-20130156756-A1 | Substituted Triazolopyridines | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-06-20 | — | — | US | disclosed |
| US-20130156756-A1 | Substituted Triazolopyridines | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-06-20 | — | — | US | disclosed |
| US-20130156756-A1 | Substituted Triazolopyridines | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-06-20 | — | — | US | disclosed |
| WO-2012160029-A1 | SUBSTITUTED TRIAZOLOPYRIDINES | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2012-11-29 | — | — | WO | disclosed |
| WO-2012143329-A1 | TRIAZOLOPYRIDINES | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2012-10-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130156756-A1 | Substituted Triazolopyridines | CCND2, CCND1, QDPR | CYP1A2 215/4885LMNA 1474/4885CYP3A4 557/4885 |
| US-10479765-B2 | Substituted N,2-diarylquinoline-4-carboxamides and the use thereof as anti-inflammatory agents | AADAC, NFKBIA, NOD2 | CYP1A2 879/4885LMNA 890/4885CYP3A4 1195/4885 |
| US-20140120087-A1 | TRIAZOLOPYRIDINES | QDPR, TBXA2R, KCNJ11 | CYP1A2 36/4885LMNA 1537/4885CYP3A4 112/4885 |
| US-20170260140-A1 | SUBSTITUTED N,2-DIARYLQUINOLINE-4-CARBOXAMIDES AND THE USE THEREOF AS ANTI-INFLAMMATORY AGENTS | AADAC, NFKBIA, NOD2 | CYP1A2 879/4885LMNA 890/4885CYP3A4 1195/4885 |
| US-20190002409-A1 | SUBSTITUTED N,2-DIARYLQUINOLINE-4-CARBOXAMIDES AND THE USE THEREOF AS ANTI-INFLAMMATORY AGENTS | AADAC, NFKBIA, NOD2 | CYP1A2 879/4885LMNA 890/4885CYP3A4 1195/4885 |
| US-10189788-B2 | Substituted N,2-diarylquinoline-4-carboxamides and the use thereof as anti-inflammatory agents | AADAC, NFKBIA, NOD2 | CYP1A2 879/4885LMNA 890/4885CYP3A4 1195/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.