Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.37 |
| ▸ | PSMB5 | P28074 | 6/20 | 0.37 |
| ▸ | TYMP | P19971 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.34 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.34 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.34 |
| ▸ | PSMB1 | P20618 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9337935 | 0.86 | ALDH1A1 (0.36) | ALDH1A1CYP3A4PTPN11PSMB5TYMP | |
| SCHEMBL11201526 | 0.84 | TYMP (0.41) | ALDH1A1CYP3A4PSMB5TYMPTDP1 | |
| SCHEMBL3502363 | 0.84 | TYMP (0.41) | ALDH1A1CYP3A4PSMB5TYMPTDP1 | |
| SCHEMBL3796623 | 0.84 | TYMP (0.41) | ALDH1A1CYP3A4PSMB5TYMPTDP1 | |
| SCHEMBL21057468 | 0.84 | TYMP (0.41) | ALDH1A1CYP3A4PSMB5TYMPTDP1 | |
| SCHEMBL3233362 | 0.84 | TYMP (0.41) | ALDH1A1CYP3A4PSMB5TYMPTDP1 | |
| SCHEMBL3233355 | 0.84 | TYMP (0.41) | ALDH1A1CYP3A4PSMB5TYMPTDP1 | |
| SCHEMBL18244171 | 0.84 | TYMP (0.41) | ALDH1A1CYP3A4PSMB5TYMPTDP1 | |
| SCHEMBL2105114 | 0.84 | TYMP (0.41) | ALDH1A1CYP3A4PSMB5TYMPTDP1 | |
| SCHEMBL119773 | 0.84 | TYMP (0.41) | ALDH1A1CYP3A4PSMB5TYMPTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2699096-A2 | METHOD FOR MOSQUITO CONTROL | Dobson, Stephen (US) | 2014-02-26 | — | — | EP | disclosed |
| WO-2012145145-A2 | METHOD FOR MOSQUITO CONTROL | DOBSON STEPHEN (US) | 2012-10-26 | — | — | WO | disclosed |