Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.33 |
| ▸ | PSMB5 | P28074 | 3/20 | 0.33 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.31 |
| ▸ | CASP3 | P42574 | 1/20 | 0.30 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.30 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.30 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.30 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
| ▸ | TYMP | P19971 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13733726 | 0.86 | ALDH1A1 (0.41) | ALDH1A1CYP3A4PTPN11PSMB5HASPIN | |
| SCHEMBL3233355 | 0.76 | TYMP (0.41) | ALDH1A1CYP3A4PSMB5CASP3SENP8 | |
| SCHEMBL2105114 | 0.76 | TYMP (0.41) | ALDH1A1CYP3A4PSMB5CASP3SENP8 | |
| SCHEMBL119773 | 0.76 | TYMP (0.41) | ALDH1A1CYP3A4PSMB5CASP3SENP8 | |
| SCHEMBL18244171 | 0.76 | TYMP (0.41) | ALDH1A1CYP3A4PSMB5CASP3SENP8 | |
| SCHEMBL3233362 | 0.76 | TYMP (0.41) | ALDH1A1CYP3A4PSMB5CASP3SENP8 | |
| SCHEMBL11201526 | 0.76 | TYMP (0.41) | ALDH1A1CYP3A4PSMB5CASP3SENP8 | |
| SCHEMBL3502363 | 0.76 | TYMP (0.41) | ALDH1A1CYP3A4PSMB5CASP3SENP8 | |
| SCHEMBL21057468 | 0.76 | TYMP (0.41) | ALDH1A1CYP3A4PSMB5CASP3SENP8 | |
| SCHEMBL3796623 | 0.76 | TYMP (0.41) | ALDH1A1CYP3A4PSMB5CASP3SENP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5290790-A | Histamine H3 antagonists, psychotropic action | NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (FR) | 1994-03-01 | — | — | US | claimed |