Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 6/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.37 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.37 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.37 |
| ▸ | PDE2A | O00408 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | BCR | P11274 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12006225 | 1.00 | P2RX7 (0.42) | P2RX7POLBHTTALDH1A1TAS1R3 | |
| SCHEMBL12005979 | 0.90 | ABL1 (0.39) | P2RX7POLBHTTMAPK1ABL1 | |
| SCHEMBL12006323 | 0.86 | HPGDS (0.39) | — | |
| SCHEMBL12005623 | 0.81 | ABL1 (0.36) | ALDH1A1MAPK1ABL1BCR | |
| SCHEMBL13730197 | 0.76 | POLB (0.42) | POLBRAB9AAADATMAPK1ABL1 | |
| SCHEMBL12005612 | 0.76 | ABL1 (0.39) | POLBAADATMAPK1ABL1BCR | |
| SCHEMBL12005011 | 0.76 | ABL1 (0.41) | ALDH1A1MAPK1ABL1BCR | |
| SCHEMBL12005013 | 0.76 | ABL1 (0.41) | ALDH1A1MAPK1ABL1BCR | |
| SCHEMBL12006296 | 0.76 | ABL1 (0.41) | ALDH1A1MAPK1ABL1BCR | |
| SCHEMBL12019742 | 0.75 | ABL1 (0.40) | ALDH1A1MAPK1ABL1BCR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2678342-A1 | N-SUBSTITUTED OXAZINOPTERIDINES AND OXAZINOPTERIDINONES | Takeda Pharmaceutical Company Limited (JP) | 2014-01-01 | — | — | EP | disclosed |
| WO-2012148548-A1 | N-SUBSTITUTED OXAZINOPTERIDINES AND OXAZINOPTERIDINONES | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2012-11-01 | — | — | WO | disclosed |