Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 11/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 11/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 11/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5113738 | 0.80 | SLC6A2 (0.36) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL9528556 | 0.80 | SLC6A2 (0.40) | SLC6A2SLC6A4SLC6A3CYP2D6 | |
| SCHEMBL476346 | 0.79 | TDP1 (0.38) | SLC6A2SLC6A3 | |
| SCHEMBL1774399 | 0.76 | SLC6A2 (0.38) | SLC6A2SLC6A4SLC6A3CYP2D6 | |
| SCHEMBL9368899 | 0.74 | BCHE (0.35) | — | |
| SCHEMBL27695148 | 0.74 | SLC6A2 (0.41) | SLC6A2SLC6A4SLC6A3CYP2D6 | |
| Bromide SCHEMBL9784507 | 0.72 | MMP9 (0.45) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL28498257 | 0.71 | SLC6A2 (0.37) | SLC6A2SLC6A4SLC6A3CYP2D6 | |
| SCHEMBL27739954 | 0.71 | SLC6A2 (0.40) | SLC6A2SLC6A4SLC6A3CYP2D6 | |
| SCHEMBL1961851 | 0.70 | SLC6A2 (0.41) | SLC6A2SLC6A4SLC6A3CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2699568-A1 | A CRYSTALLINE FORM OF A SALT OF A MORPHOLINO SULFONYL INDOLE DERIVATIVE AND A PROCESS FOR ITS PREPARATION | Piramal Enterprises Limited (IN) | 2014-02-26 | — | — | EP | disclosed |
| WO-2012143874-A1 | A PROCESS FOR THE PREPARATION OF MORPHOLINO SULFONYL INDOLE DERIVATIVES | PIRAMAL HEALTHCARE LIMITED (IN) | 2012-10-26 | — | — | WO | disclosed |
| WO-2012143879-A1 | A CRYSTALLINE FORM OF A SALT OF A MORPHOLINO SULFONYL INDOLE DERIVATIVE AND A PROCESS FOR ITS PREPARATION | PIRAMAL HEALTHCARE LIMITED (IN) | 2012-10-26 | — | — | WO | disclosed |