Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 14/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 14/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 14/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 7/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1774399 | 0.81 | SLC6A2 (0.38) | SLC6A2SLC6A4SLC6A3CYP2D6KCNH2 | |
| SCHEMBL13734320 | 0.80 | SLC6A2 (0.38) | SLC6A2SLC6A4SLC6A3CYP2D6 | |
| SCHEMBL27695148 | 0.79 | SLC6A2 (0.41) | SLC6A2SLC6A4SLC6A3CYP2D6KCNH2 | |
| Bromide SCHEMBL9784507 | 0.76 | MMP9 (0.45) | SLC6A2SLC6A4SLC6A3MEN1KMT2A | |
| SCHEMBL27739954 | 0.75 | SLC6A2 (0.40) | SLC6A2SLC6A4SLC6A3CYP2D6KCNH2 | |
| SCHEMBL1961851 | 0.74 | SLC6A2 (0.41) | SLC6A2SLC6A4SLC6A3CYP2D6TSHR | |
| SCHEMBL5841607 | 0.74 | SLC6A2 (0.39) | SLC6A2SLC6A4SLC6A3CYP2D6CYP3A4 | |
| SCHEMBL8678876 | 0.74 | MEN1 (0.36) | SLC6A2SLC6A4SLC6A3SIGMAR1TSHR | |
| SCHEMBL9523728 | 0.73 | SLC6A2 (0.40) | SLC6A2SLC6A4SLC6A3CYP2D6KCNH2 | |
| SCHEMBL2447397 | 0.72 | SLC6A2 (0.39) | SLC6A2SLC6A4SLC6A3CYP2D6CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105873920-B | As 5-HT4The indazole compound of receptor stimulating agent | 苏文生命科学有限公司 | 2018-06-08 | — | — | CN | disclosed |
| EP-0286495-B1 | MORPHOLINE DERIVATIVES, THEIR PROCESS OF PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | ADIR ET COMPAGNIE (FR) | 1993-05-12 | — | — | EP | disclosed |
| EP-0286495-A1 | Morpholine derivatives, their process of preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1988-10-12 | — | — | EP | disclosed |