Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.44 |
| ▸ | MEN1 | O00255 | 5/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8260610 | 0.84 | MAPT (0.58) | MAPTALDH1A1KMT2AMEN1TSHR | |
| SCHEMBL28443081 | 0.83 | MAPT (0.50) | MAPTALDH1A1KMT2AMEN1CHRM1 | |
| SCHEMBL28450924 | 0.83 | MAPT (0.50) | MAPTALDH1A1KMT2AMEN1CHRM1 | |
| SCHEMBL28443083 | 0.83 | MAPT (0.50) | MAPTALDH1A1KMT2AMEN1CHRM1 | |
| SCHEMBL3882849 | 0.83 | MEN1 (0.55) | MAPTALDH1A1KMT2AMEN1CHRM1 | |
| SCHEMBL2372673 | 0.81 | MEN1 (0.57) | MAPTALDH1A1KMT2AMEN1TSHR | |
| SCHEMBL8301383 | 0.81 | MEN1 (0.57) | MAPTALDH1A1KMT2AMEN1TSHR | |
| SCHEMBL25030105 | 0.81 | ALDH1A1 (0.51) | MAPTALDH1A1KMT2AMEN1TSHR | |
| SCHEMBL6634545 | 0.81 | ALDH1A1 (0.51) | MAPTALDH1A1KMT2AMEN1TSHR | |
| SCHEMBL13733825 | 0.81 | MAPT (0.51) | MAPTALDH1A1KMT2AMEN1CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012145361-A1 | MODULATORS OF THE GPR119 RECEPTOR AND THE TREATMENT OF DISORDERS RELATED THERETO | ARENA PHARMACEUTICALS, INC. (US) | 2012-10-26 | — | — | WO | disclosed |