Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.40 |
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21290242 | 0.80 | TDP1 (0.49) | KMT2ATDP1SLC6A2SLC6A3ALDH1A1 | |
| SCHEMBL13733547 | 0.79 | TDP1 (0.47) | KMT2ATDP1SLC6A2SLC6A3ALDH1A1 | |
| SCHEMBL13734316 | 0.78 | DGAT1 (0.58) | KMT2ATDP1SLC6A2SLC6A3ALDH1A1 | |
| SCHEMBL24510712 | 0.78 | ALDH1A1 (0.47) | KMT2ATDP1SLC6A2SLC6A3ALDH1A1 | |
| SCHEMBL23745082 | 0.77 | ALDH1A1 (0.46) | KMT2ATDP1SLC6A2SLC6A3ALDH1A1 | |
| SCHEMBL21923219 | 0.75 | KMT2A (0.43) | KMT2ATDP1SLC6A2SLC6A3ALDH1A1 | |
| SCHEMBL13734937 | 0.75 | DGAT1 (0.46) | KMT2ATDP1SLC6A2SLC6A3ALDH1A1 | |
| SCHEMBL25050103 | 0.72 | KMT2A (0.41) | KMT2ATDP1SLC6A2SLC6A3ALDH1A1 | |
| SCHEMBL21345457 | 0.72 | ALDH1A1 (0.57) | KMT2ATDP1SLC6A2SLC6A3ALDH1A1 | |
| SCHEMBL21887009 | 0.71 | KMT2A (0.47) | KMT2ATDP1SLC6A2SLC6A3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2699561-B1 | ANDROGEN RECEPTOR MODULATING CARBOXAMIDES | ORION CORP (FI) | 2015-06-03 | — | — | EP | disclosed |
| US-8921378-B2 | Androgen receptor modulating carboxamides | ORION CORPORATION (FI) | 2014-12-30 | — | — | US | disclosed |
| EP-2699561-A1 | ANDROGEN RECEPTOR MODULATING CARBOXAMIDES | Orion Corporation (FI) | 2014-02-26 | — | — | EP | disclosed |
| WO-2012143599-A1 | ANDROGEN RECEPTOR MODULATING CARBOXAMIDES | ORION CORPORATION (FI) | 2012-10-26 | — | — | WO | disclosed |