Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | SLC7A11 | Q9UPY5 | 1/20 | 0.36 |
| ▸ | SLC1A2 | P43004 | 4/20 | 0.34 |
| ▸ | SLC1A1 | P43005 | 4/20 | 0.34 |
| ▸ | SLC1A3 | P43003 | 3/20 | 0.34 |
| ▸ | GRIK1 | P39086 | 4/20 | 0.33 |
| ▸ | ENPEP | Q07075 | 3/20 | 0.33 |
| ▸ | GRIK2 | Q13002 | 3/20 | 0.33 |
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3896559 | 1.00 | PTGS1 (0.60) | PTGS1ALDH1A1MAPTSLC7A11SLC1A2 | |
| SCHEMBL4768361 | 1.00 | PTGS1 (0.60) | PTGS1ALDH1A1MAPTSLC7A11SLC1A2 | |
| SCHEMBL3896562 | 1.00 | PTGS1 (0.60) | PTGS1ALDH1A1MAPTSLC7A11SLC1A2 | |
| Hydrochloric Acid SCHEMBL6352890 | 0.98 | PTGS1 (0.58) | PTGS1ALDH1A1MAPTSLC7A11SLC1A2 | |
| SCHEMBL6262500 | 0.83 | PTGS1 (0.56) | PTGS1ALDH1A1MAPTSLC7A11SLC1A2 | |
| Hydrochloric Acid SCHEMBL6341117 | 0.81 | PTGS1 (0.54) | PTGS1ALDH1A1MAPTSLC7A11SLC1A2 | |
| SCHEMBL21480206 | 0.80 | PTGS1 (0.58) | PTGS1ALDH1A1MAPTSLC7A11GRIK1 | |
| SCHEMBL6263592 | 0.79 | MAPT (0.52) | PTGS1ALDH1A1MAPTSLC1A2SLC1A1 | |
| SCHEMBL22836202 | 0.79 | PTGS1 (0.56) | PTGS1ALDH1A1MAPTSLC7A11SLC1A2 | |
| SCHEMBL6501664 | 0.79 | PTGS1 (0.56) | PTGS1ALDH1A1MAPTSLC7A11SLC1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210380952-A1 | Method to Produce Virus in Cultured Cells Supplemented With Alpha-Ketoglutarate | UNIV PRINCETON (US) | 2021-12-09 | — | — | US | claimed |
| EP-3656855-A1 | METHOD TO PRODUCE VIRUS IN CULTURED CELLS | The Trustees of Princeton University (US) | 2020-05-27 | — | — | EP | claimed |
| EP-2699672-B1 | METHOD TO PRODUCE VIRUS IN CULTURED CELLS | UNIV PRINCETON (US) | 2019-12-25 | — | — | EP | claimed |
| US-20190218524-A1 | Method to Produce Virus in Cultured Cells Supplemented With Alpha-Ketoglutarate | THE TRUSTEES OF PRINCETON UNIVERSITY | 2019-07-18 | — | — | US | claimed |
| US-20180298348-A1 | Method to Produce Virus in Cultured Cells Supplemented With Alpha-Ketoglutarate | UNIV PRINCETON (US) | 2018-10-18 | — | — | US | claimed |
| US-9212349-B2 | Method to produce virus in cultured cells | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2015-12-15 | — | — | US | claimed |
| US-20140113353-A1 | Method to Produce Virus in Cultured Cells | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2014-04-24 | — | — | US | claimed |
| EP-2699672-A1 | METHOD TO PRODUCE VIRUS IN CULTURED CELLS | The Trustees of Princeton University (US) | 2014-02-26 | — | — | EP | claimed |
| WO-2013158706-A1 | METHOD TO PRODUCE VIRUS IN CULTURED CELLS SUPPLEMENTED WITH ALPHA-KETOGLUTARATE | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2013-10-24 | — | — | WO | claimed |
| WO-2012145375-A1 | METHOD TO PRODUCE VIRUS IN CULTURED CELLS | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2012-10-26 | — | — | WO | claimed |
| US-20210380952-A1 | Method to Produce Virus in Cultured Cells Supplemented With Alpha-Ketoglutarate | UNIV PRINCETON (US) | 2021-12-09 | — | — | US | disclosed |
| EP-3656855-A1 | METHOD TO PRODUCE VIRUS IN CULTURED CELLS | The Trustees of Princeton University (US) | 2020-05-27 | — | — | EP | disclosed |
| EP-2699672-B1 | METHOD TO PRODUCE VIRUS IN CULTURED CELLS | UNIV PRINCETON (US) | 2019-12-25 | — | — | EP | disclosed |
| US-20190218524-A1 | Method to Produce Virus in Cultured Cells Supplemented With Alpha-Ketoglutarate | THE TRUSTEES OF PRINCETON UNIVERSITY | 2019-07-18 | — | — | US | disclosed |
| US-20180298348-A1 | Method to Produce Virus in Cultured Cells Supplemented With Alpha-Ketoglutarate | UNIV PRINCETON (US) | 2018-10-18 | — | — | US | disclosed |
| US-20150240215-A1 | METHOD TO PRODUCE VIRUS IN CULTURED CELLS SUPPLEMENTED WITH ALPHA-KETOGLUTARATE | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2015-08-27 | — | — | US | disclosed |
| US-20140113353-A1 | Method to Produce Virus in Cultured Cells | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2014-04-24 | — | — | US | disclosed |
| EP-2699672-A1 | METHOD TO PRODUCE VIRUS IN CULTURED CELLS | The Trustees of Princeton University (US) | 2014-02-26 | — | — | EP | disclosed |
| WO-2013158706-A1 | METHOD TO PRODUCE VIRUS IN CULTURED CELLS SUPPLEMENTED WITH ALPHA-KETOGLUTARATE | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2013-10-24 | — | — | WO | disclosed |
| WO-2012145375-A1 | METHOD TO PRODUCE VIRUS IN CULTURED CELLS | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2012-10-26 | — | — | WO | disclosed |