Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | SLC7A11 | Q9UPY5 | 1/20 | 0.36 |
| ▸ | SLC1A2 | P43004 | 4/20 | 0.34 |
| ▸ | SLC1A1 | P43005 | 4/20 | 0.34 |
| ▸ | SLC1A3 | P43003 | 3/20 | 0.34 |
| ▸ | GRIK1 | P39086 | 4/20 | 0.33 |
| ▸ | ENPEP | Q07075 | 3/20 | 0.33 |
| ▸ | GRIK2 | Q13002 | 3/20 | 0.33 |
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13736271 | 1.00 | PTGS1 (0.60) | PTGS1ALDH1A1MAPTSLC7A11SLC1A2 | |
| SCHEMBL3896559 | 1.00 | PTGS1 (0.60) | PTGS1ALDH1A1MAPTSLC7A11SLC1A2 | |
| SCHEMBL3896562 | 1.00 | PTGS1 (0.60) | PTGS1ALDH1A1MAPTSLC7A11SLC1A2 | |
| Hydrochloric Acid SCHEMBL6352890 | 0.98 | PTGS1 (0.58) | PTGS1ALDH1A1MAPTSLC7A11SLC1A2 | |
| SCHEMBL6262500 | 0.83 | PTGS1 (0.56) | PTGS1ALDH1A1MAPTSLC7A11SLC1A2 | |
| Hydrochloric Acid SCHEMBL6341117 | 0.81 | PTGS1 (0.54) | PTGS1ALDH1A1MAPTSLC7A11SLC1A2 | |
| SCHEMBL21480206 | 0.80 | PTGS1 (0.58) | PTGS1ALDH1A1MAPTSLC7A11GRIK1 | |
| SCHEMBL6263592 | 0.79 | MAPT (0.52) | PTGS1ALDH1A1MAPTSLC1A2SLC1A1 | |
| SCHEMBL22836202 | 0.79 | PTGS1 (0.56) | PTGS1ALDH1A1MAPTSLC7A11SLC1A2 | |
| SCHEMBL6501664 | 0.79 | PTGS1 (0.56) | PTGS1ALDH1A1MAPTSLC7A11SLC1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140112976-A1 | Cyclic Peptides with an Anti-Neoplasic and Anti-Angiogenic Activity | CENTRO DE INGENIERIA GENETICA BIOTECNOLOGIA (CU) | 2014-04-24 | — | — | US | claimed |
| EP-2690107-A2 | CYCLIC PEPTIDES WITH AN ANTI-NEOPLASIC AND ANTI-ANGIOGENIC ACTIVITY | Centro De Ingenieria Genetica Y Biotecnologia (CU) | 2014-01-29 | — | — | EP | claimed |
| CN-103534265-A | Cyclic peptides with an anti-neoplasic and anti-angiogenic activity | CT INGENIERIA GENETICA BIOTECH | 2014-01-22 | — | — | CN | claimed |
| CN-100522153-C | Use of carbonyl scavengers for the preparation of a medicament for inducing or accelerating cell death in abnormal cells | UNIV ARIZONA STATE (US) | 2009-08-05 | — | — | CN | claimed |
| EP-1720538-B1 | METHOD FOR INDUCING CELL DEATH WITH CARBONYL SCAVENGERS | UNIV ARIZONA (US) | 2008-11-12 | — | — | EP | claimed |
| EP-2690107-B1 | CYCLIC PEPTIDES WITH AN ANTI-NEOPLASIC AND ANTI-ANGIOGENIC ACTIVITY | CT INGENIERIA GENETICA BIOTECNOLOGIA (CU) | 2017-08-02 | — | — | EP | disclosed |
| US-9375459-B2 | Cyclic peptides with an anti-neoplasic and anti-angiogenic activity | CENTRO DE INGENIERIA GENETICA BIOTECNOLGIA (CU) | 2016-06-28 | — | — | US | disclosed |
| CN-103534265-B | There is antitumor and form the cyclic peptide with anti-angiogenesis activity | 遗传工程与生物技术中心 | 2016-06-08 | — | — | CN | disclosed |
| US-20140112976-A1 | Cyclic Peptides with an Anti-Neoplasic and Anti-Angiogenic Activity | CENTRO DE INGENIERIA GENETICA BIOTECNOLOGIA (CU) | 2014-04-24 | — | — | US | disclosed |
| EP-2690107-A2 | CYCLIC PEPTIDES WITH AN ANTI-NEOPLASIC AND ANTI-ANGIOGENIC ACTIVITY | Centro De Ingenieria Genetica Y Biotecnologia (CU) | 2014-01-29 | — | — | EP | disclosed |
| CN-103534265-A | Cyclic peptides with an anti-neoplasic and anti-angiogenic activity | CT INGENIERIA GENETICA BIOTECH | 2014-01-22 | — | — | CN | disclosed |
| CN-100522153-C | Use of carbonyl scavengers for the preparation of a medicament for inducing or accelerating cell death in abnormal cells | UNIV ARIZONA STATE (US) | 2009-08-05 | — | — | CN | disclosed |
| EP-1720538-B1 | METHOD FOR INDUCING CELL DEATH WITH CARBONYL SCAVENGERS | UNIV ARIZONA (US) | 2008-11-12 | — | — | EP | disclosed |
| CN-1964710-A | Method for inducing cell death with carbonyl scavengers | UNIV ARIZONA (US) | 2007-05-16 | — | — | CN | disclosed |
| US-7217739-B2 | Method for inducing cell death with carbonyl scavengers | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) | 2007-05-15 | — | — | US | disclosed |
| EP-1720538-A4 | METHOD FOR INDUCING CELL DEATH WITH CARBONYL SCAVENGERS | UNIV ARIZONA (US) | 2007-04-11 | — | — | EP | disclosed |
| EP-1720538-A1 | METHOD FOR INDUCING CELL DEATH WITH CARBONYL SCAVENGERS | The Arizona Board of Regents on behalf of the University of Arizona (US) | 2006-11-15 | — | — | EP | disclosed |
| WO-2005084659-A1 | METHOD FOR INDUCING CELL DEATH WITH CARBONYL SCAVENGERS | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) | 2005-09-15 | — | — | WO | disclosed |
| US-20050197400-A1 | Method for inducing cell death with carbonyl scavengers | NIADYNE, INC. | 2005-09-08 | — | — | US | disclosed |